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Contraindications for use. Additional substances that are part of Duphaston

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Many women experience fertility problems or complications during pregnancy. Scientists have found that one of the factors provoking such deviations is a hormonal imbalance or lack of progesterone in a woman's body. To address these issues, as well as for the treatment and prevention of infertility, normalization of ovulation, doctors prescribe Duphaston during or before pregnancy.

Duphaston - instructions for use during pregnancy

The ovaries and adrenal glands in the body of a woman perform one of the main roles - they produce the steroid hormone progesterone necessary for normal menstruation and successful conception. However, for various reasons, failures in the operation of these systems can occur, which will lead to a decrease in the level of the hormone in the woman's blood. In this case, for the successful bearing of the fetus, a medical drug Duphaston.

It is an analogue of the hormone progesterone of natural origin and is well accepted by the woman's body. The drug does not affect the functioning of the liver, but at the same time normalizes the tone of the smooth muscles of the uterus, without disturbing the menstrual cycle and ovulation. Such an effect on the body increases the chances of successfully bearing a baby: it prevents the risks of miscarriages or the freezing of the embryo. If a woman was diagnosed with increased uterine tone, then when taking these pills, in 85% of cases the child can be saved.

Composition and form of release

The medicine is sold in cardboard packs of 20 or 14 tablets. In addition to blisters, the box contains detailed instructions for use. The tablets themselves are small in shape, round with a division in the middle. On the back of the package there is information about the manufacturer, storage rules and composition. According to this, the basis of 1 tablet contains:

The action of the drug

When using the drug, the deficiency of natural hormones is compensated, due to which the percentage of spontaneous miscarriage in the first weeks of pregnancy, the risks of developing fetal defects and abnormalities in the formation of the placental layer are significantly reduced. Additional intake of synthetic progesterone in the body normalizes the hormonal background in a woman, provides a normal nutritional and oxygen balance for the fetus.

Absorption of active components into the blood occurs in the intestinal mucosa. The maximum concentration of substances is reached 1.5-2 hours after taking the medication. The half-life of the active ingredients occurs in the liver, and the remains of the drug are excreted by the kidneys along with urine. The duration of the period of their complete elimination is 70 hours.

Indications for use

The main indication for the appointment of Duphaston is a deficiency in the body of natural progesterone. Before starting treatment, a woman should be tested to confirm suspicions. According to instructions, it is advisable to take pills:

  • in the treatment of violations of the monthly cycle - delayed menstruation, normalization of the second stage of the cycle;
  • with severe premenstrual syndrome - pain in the abdomen, lower back, migraines;
  • if there is a threat of termination of early pregnancy;
  • with endometriosis;
  • for the treatment of infertility;
  • to preserve the fetus;
  • threatened or habitual abortion.

Duphaston in early pregnancy

During pregnancy, the drug will compensate for the lack of progesterone and take over its functions. The drug will support the activity of the corpus luteum during conception, relax the endometrium of the uterus, and have an immunosuppressive effect so that the body does not perceive the fertilized egg as a foreign body. If at the beginning of pregnancy there are signs of spontaneous abortion or other threat of miscarriage, taking a synthetic hormone is useful for maintaining the pregnancy.

At a later date

The duration of taking the tablets is determined by the doctor. As a rule, the medication is prescribed before conception and it is recommended to continue drinking until the 16-20th week of pregnancy. However, if there are certain indications, the doctor may prescribe Duphaston in late pregnancy. One of the reasons is the increased tone of the uterus, when there are risks of premature birth. Anyway the drug should be stopped before 36 weeks of pregnancy.

How to take Duphaston

The dosage of Duphaston and the course of treatment are chosen individually by the doctor in accordance with the test data, the general picture and the patient's complaints. As a rule, when planning a pregnancy, the drug is started a few weeks before conception and continues up to the 16th week. If the level of hormones has decreased in the later stages of bearing a baby, treatment is continued until 24-25 weeks.

According to the instructions, the scheme for taking the tablets is as follows:

  • With the growth of the endometrium, take 1 tablet of Duphaston 2-3 times a day, constantly or from the last day of the menstrual cycle to day 25.
  • With a high level of estrogen hormones, but a low level of the hormone progesterone in the luteal phase, they drink 1 tablet of the drug from the moment of ovulation to the 25th day of the cycle. The recommended course of treatment is 6 months, and after conception - throughout the first trimester of pregnancy.
  • With the threat of miscarriage, spontaneous abortion or other pathologies, 4 tablets are prescribed for the first time, then 1 piece 3 times a day until the problem is eliminated.
  • To prevent or eliminate uterine bleeding, doctors recommend taking 1 tablet 2 times a day for 7 days.

Missed medication

You need to drink tablets regularly, without missing a single day. If during the treatment of certain problems you accidentally forgot to take Duphaston, according to the instructions, you need to drink the prescribed dose of the drug within the next 6 hours. If more time has passed since taking the recommended dose, then you should not drink an additional pill, you need to continue treatment according to the prescribed scheme.

How to cancel Duphaston during pregnancy

Cancellation of hormone therapy should be gradual and only on the recommendation of the attending physician, when the level of progesterone, according to the laboratory, returned to normal. A sharp rejection of any hormonal medication can lead to side effects and cause irreversible reactions in the body. Duphaston should be canceled during pregnancy according to the following scheme:

  • If a woman has previously taken 2 tablets per knock, then the dosage of the drug should be reduced to 1.5 tablets.
  • A week later, the same dosage should be reduced to 1 tablet and so on until the drug is completely abandoned.

special instructions

The combined use of the drug with drugs containing estrogen hormones should be administered with caution to patients with renal insufficiency, heart or vascular disease, epilepsy, diabetes mellitus or chronic headaches. The active components of Duphaston do not affect the speed of thinking and reaction. When undergoing hormonal therapy, you need to regularly undergo a mammogram examination.

Interaction with drugs

Throughout treatment, and especially at the beginning of pregnancy, Duphaston for pregnant women should not be combined with broad-spectrum antibiotics, sleeping pills or antiepileptic drugs, such as Rifampicin or Phenobarbital. Otherwise, Duphaston may not have the desired effect. Cases of incompatibility of this medicinal product with other medicines are unknown.

Side effects and overdose

Pregnancy against the background of Duphaston, as a rule, proceeds without consequences for the mother and child. However, in rare cases, side effects may occur that are easily eliminated by dosage adjustments. Among the negative reactions there are such cases:

  • When using too small doses, spotting from the uterus may appear.
  • Sometimes there is soreness of the chest, discomfort in the epigastric region and the appearance of headaches.
  • Very rarely, skin rashes, accumulation of fluid - swelling of the limbs and other allergic reactions are possible.
  • In some women, when taking hormonal drugs, sexual desire decreases or increases.
  • Cases of overdose with Duphaston during pregnancy have not been identified.

Contraindications

Dufaston and pregnancy are two inseparable concepts. However, with caution, the drug is prescribed if in the anamnesis of a pregnant woman there were violations in the liver - jaundice, severe pruritus. The second most important indicator for drug withdrawal is the tendency to allergic reactions to one or more substances from the composition. The drug is stopped if the pregnancy is frozen, bleeding of unknown origin or ectopic pregnancy occurs. It is strictly forbidden to take pills in the presence of:

  • Rotor or Dubin-Jones disease;
  • severe liver disease;
  • malignant neoplasms of the mammary glands or genital organs;
  • severe thrombophlebitis or a tendency to thrombosis.

Terms of sale and storage

In pharmacies, Dufaston is released upon presentation of a prescription from a gynecologist. It is necessary to store tablets at a temperature from 0 to 30 degrees Celsius in a place protected from sunlight and children. Duphaston should not be taken after the expiry date which is stated on the carton. Under all conditions, the maximum shelf life is 5 years.

Duphaston's analogs

Synonymous drugs should not only differ from Duphaston in price, but also have similar properties and principles of influence on the body of a pregnant woman. At the same time, some medicines may have a distinctive composition, which is a plus for those who suffer from individual intolerance to dydrogesterone or other substances. At the risk of miscarriage or violations in the formation of the placenta, the doctor may prescribe one of the following Duphaston analogues:

  • Dufaston;
  • Dydrogesterone;
  • Utrozhestan;
  • Progesterone;
  • lutein;
  • Injesta.

Duphaston price

You can buy the drug at any pharmacy at an affordable price or order home delivery of the drug from an online store. Upon receipt of the goods, you must provide the seller with the original prescription from the doctor. How much Dufaston costs in Moscow pharmacies is indicated in the table:

In the absence of pregnancy or a problem with miscarriage, women are often prescribed hormone replacement therapy.

Dufaston, a drug that replenishes, responsible for the onset of pregnancy and the creation of optimal conditions for the further development of the fetal egg.

The “pregnancy hormone”, progesterone, is responsible for preparing the endometrium of the uterus to receive a fertilized egg. Almost the entire first trimester, the production of the enzyme occurs at the expense of, which ensures the vital activity of the zygote.

Starting from the second trimester, the production of progesterone becomes one of the main tasks of the placenta. It turns out that the enzyme is needed by the body for the entire period of bearing a child.

Also, the hormone plays an important role in conception, since the onset of ovulation depends on it. Thanks to progesterone, the muscles of the uterus relax, and it does not interfere with the implantation of the embryo.

Therefore, it is so important to eliminate the enzyme deficiency before conception and monitor its concentration during pregnancy if a woman has previously been diagnosed with a miscarriage problem.

To compensate for the lack of the hormone, preparations were created that completely repeat the composition of the enzyme. Among them is Duphaston, a synthetic analogue of progesterone.

The drug is produced in the form of coated tablets. Each form contains 10 mg of dydrogesterone, the active substance. In the list of auxiliary ingredients, you can read about the presence of lactose monohydrate, colloidal silicon dioxide, magnesium stearate, corn starch. The shell consists of hypromellose, titanium dioxide, polyethylene glycol.

The drug goes on sale in cardboard packs, in which there is a blister with 20 tablets.

Currently, there are several analogues of progesterone. Why is Duphaston preferred in some cases?

When comparing the characteristics of this tool and, for example, the disadvantages and advantages of both drugs become obvious:

  • For the production of Utrozhestan, vegetable raw materials are used. The drug is a natural analogue of the enzyme, in contrast to the fully synthetic Duphaston. The structure and composition of Utrozhestan are identical to the hormone produced by the woman's body.
  • The naturalness of Utrozhestan sometimes becomes a disadvantage, since the drug has a negative effect on the functionality of the liver and is contraindicated in diseases of the organ.
  • Unlike Utrozhestan, the synthetic analogue is considered practically harmless and can be safely taken during pregnancy.
  • Utrozhestan is available in the form of capsules, which can be taken intravaginally or orally. Duphaston is produced only in tablet form, which can make it difficult to take the drug with severe toxicosis.
  • Taking Duphaston does not cause side effects such as drowsiness, irritability, and a constant feeling of weakness. But, Utrozhestan practically does not affect weight.
  • If, during breastfeeding, Utrozhestan can be used in exceptional cases, Duphaston is prohibited, since the drug easily penetrates into the mammary glands and is present in milk.

Which of the progesterone analogues will be effective, the doctor decides based on the woman's history and depending on the course of pregnancy.

Planning pregnancy with Duphaston

Duphaston tablets are often prescribed. The drug is quickly absorbed into the blood from the digestive tract.

The maximum concentration of the enzyme in plasma is observed already 2 hours after ingestion.

A special scheme has been developed according to which it is recommended to drink Duphaston, just at the stage of pregnancy planning, in order to ensure a sufficient level of progesterone.

Daily during this time, 1 tablet of Duphaston is taken. If necessary, the dosage of Dufaston can be increased.

In order for the pregnancy to proceed normally, it is necessary to continue treatment for six months and only after that plan conception. This also applies to preparation for in vitro fertilization.

Before the course of treatment, a woman should undergo an examination to determine the level of progesterone in the middle of the 2nd phase of the cycle.

In order for the analysis of the blood sample to be accurate, you need to know when she is ovulating. To do this, it is recommended to monitor the basal temperature.

With irregular periods, it is advisable to take blood for the determination of progesterone twice. The analysis will allow you to clarify the dosage of the drug and make the necessary changes to the regimen.

Pregnancy against the background of Duphaston occurs after 3-6 months of treatment.

The drug is taken every cycle, starting immediately from the 1st day following ovulation.

If pregnancy has not occurred, after the next ovulation, it is necessary to continue the course of treatment until conception occurs.

Stop taking only after the arrival of menstruation, making sure that there is no pregnancy. If there is a delay, the drug should be continued, as abrupt withdrawal provokes.

If pregnancy does not occur within a year after the first course, treatment tactics should be changed, a thorough diagnosis should be carried out, and another progesterone analogue should be used. Cancellation of Duphaston in this case does not pose any danger.

At conception and normal production of progesterone, the decrease in the dosage of Duphaston should take place smoothly. How exactly the drug should be discontinued is decided by the doctor based on the analyzes of the pregnant woman.

Most often, taking a hormonal agent continues until 18-20 weeks, when the placenta develops sufficiently and can independently provide the body with an enzyme.

The appointment of Duphaston with the threat of miscarriage

In early pregnancy, progesterone deficiency may begin. In this case, it is recommended to take Dufaston to maintain pregnancy and maintain the level of the desired enzyme.

How to take Duphaston during pregnancy?

The drug is prescribed according to individual indications. As a rule, the dose is 10 mg per day. But in special cases, the dosage can be increased to 30 and even 40 mg.

In order to prevent the death of the fetus, it is necessary to inform the doctor about the pulling painful sensations at their first appearance.

  • with endometriosis - the growth of the endometrium of the uterus beyond its limits;
  • with infertility associated with progesterone deficiency;
  • with frequent miscarriages due to progesterone deficiency;
  • if there is a threat of miscarriage;
  • with irregular menstruation;
  • in the presence of premenstrual syndrome;
  • with uterine dysfunctional bleeding;
  • with primary and secondary aminorrhea.

As hormone replacement therapy, Duphaston is prescribed for hormonal imbalances caused by a decrease in ovarian functionality, as well as in the absence of a corpus luteum.

Prophylactically, the drug can be used if the woman's history is present.

Duphaston also finds application in the treatment of ovarian cysts. In a small amount, progesterone is produced by the adrenal glands, therefore, with a decrease in their functionality, Duphaston can be used to adjust the hormonal background.

Personal experience

I drank Duphaston twice - I was prescribed it during my first and last pregnancy. The first time he was prescribed to me for a period of almost 13 weeks. There were no special prescriptions, but because of past unsuccessful experiments, the doctors simply played it safe.

I read somewhere that the drug can cause late pregnancy fading. This is wrong. I drank the course up to the 20th week inclusive. A friend was also prescribed "Duphaston" until the 27th week, because. the fetus was located incorrectly and blocked the bottom of the pharynx. In each case, the appointment is individual. I took 2 tablets for the first month, then 1 tablet. The drug is expensive, so I was allowed to reduce the dose, and there was no need to drink it so often.

In the second case, I arbitrarily refused Duphaston. By this time, there are already three children. I didn’t want to stuff the fetus with various hormones, especially since there were enough vitamins. It was prescribed to me as an additional complex. I just didn't want to take hormone pills. From 6 to 13 weeks, as the drug was prescribed, she drank regular folic acid instead.

As far as I remember, Duphaston can be prescribed to those who are threatened with a miscarriage. It is a pity that I did not take it when it was really necessary. Therefore, girls, carefully and attentively treat your health and what you are prescribed.

Tatiana, 29.

Contraindications for use

Duphaston is safe for a developing fetus, but the drug has side effects that lead to discomfort for a woman:

  • on the ingredients that make up the drug;
  • increased destruction of red blood cells;
  • migraine;
  • a slight decrease in the functionality of the liver, manifested by icterus of the skin and mild pain in the area of ​​the right hypochondrium;
  • breakthrough bleeding, disappearing with an increase in the dosage of the drug;
  • high sensitivity of the mammary glands;
  • hives;
  • peripheral edema.

Is Dufaston harmful?

A contraindication to taking Duphaston is lactation and hypersensitivity. With caution, the remedy is prescribed in the presence of skin itching or allergies during previous pregnancies, since sometimes Duphaston can provoke Quincke's edema.

Treatment with Dufaston allows a woman to conceive a long-awaited child and eliminate the threat of spontaneous abortion at an early stage. However, if there are pronounced side effects, you should consult a gynecologist who will prescribe a different progesterone analogue.

In many patients, the appointment of hormonal drugs causes negative emotions. With a deficiency of progesterone, there is a threat of termination of pregnancy. Hormone therapy has long been used in gynecology and obstetrics. The drug "Duphaston" is safe during pregnancy. It is an analogue of natural progesterone. This is a new highly effective hormonal drug that is devoid of serious side effects.

Description

The drug is available in tablets of 10 mg. The molecular structure of the active substance (dydrogesterone) and its physical properties are very close to natural progesterone. The instructions for use say that the medicine does not have a contraceptive effect.

The drug is prescribed for such conditions that are accompanied by a deficiency of progesterone:

  • infertility with luteal insufficiency;
  • premenstrual syndrome;
  • endometriosis;
  • risk of miscarriage;
  • irregular menstruation;
  • secondary amenorrhea;
  • uterine bleeding.

The medicine is also taken during menopause.

Mechanism of action

Progesterone is a hormone that affects the process of conception and the maintenance of pregnancy. It is produced when the egg is fertilized. In order for it to successfully attach to the wall of the uterus, progesterone is needed. The hormone also helps prepare the mammary glands. If its level decreases, a miscarriage may occur.

In order to make up for the lack of a hormone, Duphaston is prescribed during pregnancy. Dydrogesterone is a synthetic hormone that replaces natural progesterone. It is essential for the survival of the embryo.

The medication is prescribed only after determining the level of progesterone. Analyzes should be done in the second half of the menstrual cycle. The results may not be objective if the studies are carried out ahead of schedule or later.

In what cases is the drug prescribed?


With the threat of miscarriage

The first trimester of pregnancy is considered the most difficult. During this period, the early development of the embryo occurs and the placenta is formed. With the threat of termination of pregnancy, hormone therapy is also prescribed. Doses are selected individually depending on the cause of the threat of miscarriage. Hormonal therapy in the early stages is not indicated. The medicine is prescribed from 6-7 weeks 2 times a day, 10 mg.

The gynecologist can change the treatment regimen for threatened abortion by prescribing 4 tablets at once for the first dose. In the following days, take 1 tablet every 8 hours. The dosage is determined by the doctor, after mandatory blood tests.

Repeated miscarriages

Miscarriages most often occur during the laying of vital organs. During this period, there is a high probability of a missed pregnancy. One of the most common causes is hormonal imbalance. If there has been a miscarriage before, Duphaston may be prescribed during pregnancy. One miscarriage does not mean that the medicine should be taken.

During IVF preparation

"Dufaston" is prescribed for the transfer of the embryo into the uterine cavity. Patients with infertility have altered ovarian function and reduced testosterone levels. The drug occupies a special place in the embryo donation program. The medicine prepares the uterus for the implantation process. All patients in the preparation of IVF must take "Dufaston". Tablets are prescribed to drink 21 days before the transfer, and for 12 weeks after.

The drug can be taken for a long time, and all thanks to its advantages:

  • no side effects;
  • high bioavailability.

When planning a pregnancy

The drug helps in the treatment of infertility. You can read about this in the instructions. The annotation says that the medicine must be taken at 10 mg. It should be started to drink from the 14th to the 25th day of the cycle. It is recommended to take the drug for six months.

It should be remembered that only a doctor can determine the required dosage based on the results of the tests and all studies. Treatment is carried out under the constant supervision of a gynecologist. He must be informed if pregnancy has occurred. You should not stop taking the drug on your own, as this is dangerous for the fetus and mother. With a sharp decrease in the level of the hormone, there is a risk of abortion. The gynecologist will adjust the dose and determine how much longer you need to take the pills.

How to use?

The drug "Dufaston" during pregnancy is prescribed by a doctor, which means that he will select the regimen of admission individually. If a woman drank the medicine before conception, then she continues to do so in the early stages of pregnancy. Duphaston is taken 1 tablet 2 times a day. The placenta is formed by 16-18 weeks of pregnancy. By this time, the need to take the medicine disappears.

How much more to drink the drug is determined only by the gynecologist. He can prescribe Duphaston during early pregnancy, as well as after the 20th week. During this period, the placental layer is already formed and itself begins the synthesis of progesterone. Teratogenic effects of the drug on the fetus in the later stages are excluded. After 36 weeks, it is stopped taking.

What to do if the patient forgot about taking Duphaston during pregnancy? The medicine must be drunk in the near future (6 hours). The dose should not be increased even if more time has passed.

How to cancel the drug?

The drug is taken up to 16-18 weeks of pregnancy. Tablets are drunk in the dosage calculated by the doctor. After that, the use of the drug is gradually reduced, reducing the dose by 0.5-1 tablet per week. Reducing the dose when taking Duphaston during pregnancy is possible if the hormonal level is normal.

Contraindications and side effects

"Dufaston" is a safe medicine, but it should not be taken without the supervision and prescription of a doctor. The instructions for the drug indicate contraindications:

  • diseases and disorders of the liver;
  • hereditary Dubin-Jones and Rotor syndromes;
  • allergic reactions to the components of the drug;
  • neoplasms of the mammary glands and genital organs;
  • thrombophlebitis and a tendency to thrombosis.

Sometimes "Duphaston" can cause:

  • rash and itching;
  • dizziness and drowsiness.

What you need to know about the drug

The cost of the drug

Tablets are sold in a pack of 20 pieces. Prices in Moscow pharmacies are 487-604 rubles, and for example, in Khabarovsk, you will have to pay 517.60 for a medicine. In an online pharmacy, you can buy a drug for 470–553 rubles. The price is about the same everywhere.

Medication safety

"Dufaston" does not have a negative effect on ovulation. It does not have a contraceptive effect. Most often, it is prescribed from the 16th day (the second phase of the cycle). The drug does not change carbohydrate and lipid metabolism. Tablets affect only progesterone levels.

The first trimester is the most important period that determines the further development of pregnancy. It is at this time that the woman's body is actively preparing for motherhood, all conditions are created for the formation and development of the baby. If there are malfunctions in the endocrine system, drug therapy is often prescribed.

Duphaston during pregnancy in the early stages makes up for the lack of the most important hormone - progesterone. It is he who allows you to relax the muscle fibers, protecting them from spontaneous contractions. Prepares the body, reducing its immune defenses, to secure the amniotic egg in the uterine cavity. Thanks to advances in medicine, today it is possible to normalize the condition of the expectant mother and baby in the event of deviations.

Operating principle

Many pregnant women try to avoid taking any medication, believing that this will affect the formation of the fetus. The drug Dufastan is completely safe for both the woman and her child. This is an analogue of natural progesterone, the very main hormone, without which the most important thing cannot be realized - conception, gestation and the birth of a new life. Normally, its enhanced synthesis begins after the fertilization of the egg, when it makes its way to the main destination - the uterus. In the cavity of the muscular organ, the amniotic egg is fixed, then the embryo will develop and grow, turning into a fetus.

If, for any reason, the level of progesterone falls, this leads to a threat to the life of the embryo. Therefore, this drug is prescribed, it makes up for the deficiency until the placenta takes over the functions of hormone synthesis. This happens at about 20 obstetric weeks, and after that there is no need to maintain medication. In rare cases, the drug is taken longer, but after 22 weeks the threat of miscarriage disappears, we are already talking about the risk of premature birth. The tablets are absolutely safe, they do not affect lipid and carbohydrate metabolism, only the effect on hormone levels is exerted.

Indications for use

During pregnancy, a drug is prescribed to reduce spontaneous interruption. Thanks to its action, the uterus relaxes, spasms and bleeding stop. Favorable conditions are also created for the formation of the mucous membrane - the future placenta, whose functions in the early stages are performed by the corpus luteum.

Another reason for the appointment may be chronic endometritis. This is a special state of the female body's immune system, in which the embryo is perceived as a foreign body that is dangerous. If timely diagnosis and appropriate therapy is not carried out, there is a risk of spontaneous miscarriage.

Reception Duphaston

Very often, the drug is prescribed in the period of preparation for conception, when there are medical indications. In such cases, the woman continues to take the entire first trimester and after the onset of fertilization. Enough for 1 tablet 2 times a day, but the scheme may vary, depending on the individual characteristics of the pregnant woman. It is impossible to introduce changes into the prescriptions of the gynecologist on your own, especially to increase or decrease the doses. Even if the expectant mother forgot to drink the drug on time, she can do this in the next 6 hours, the hormone level in the blood will not change dramatically.

There is no need to take the drug with a formed placenta (18 weeks). If the hormone levels are normal, Dufaston is canceled gradually, the dosage is reduced to 1 tablet per week. The rapid completion of the reception can provoke bleeding and subsequent miscarriage.

Consequences of admission

Despite the fact that the drug is very similar in its molecular structure to progesterone, individual reactions of the body are possible. This is the minimum discomfort, which allows you to do the most important thing - to save the pregnancy.

Side effects:

  • increased sensitivity of the mammary glands;
  • uterine bleeding (dosage changes);
  • pain in the abdomen;
  • weakness, malaise;
  • headaches, migraine;
  • insomnia;
  • itching, rash, urticaria (very rare);
  • hemolytic anemia (isolated cases);
  • edematous syndrome.

In addition, there are conditions in which the drug should not be taken.

Contraindications:

  • diabetes;
  • diseases of the excretory system;
  • rare hereditary diseases;
  • malfunctions of the cardiovascular system;
  • individual intolerance.

Duphaston is not to be taken with medications containing estrogen. All appointments are controlled only by a doctor.

If the pregnant woman made a mistake with the dose and took more than prescribed, gastric lavage is necessary. Special antidotes do not exist, only the treatment of the symptoms that have arisen is carried out. In any case, if adverse reactions or overdose occur, you should seek medical help.