Pimafucin during pregnancy: safe treatment of fungal diseases. Photo gallery: antifungal drugs for the treatment of thrush. The value of medical care

Pimafucin during pregnancy is one of the few approved drugs for the treatment of thrush. He for a long time used in medical practice and has established itself as a safe remedy.

In expectant mothers, the treatment of candidiasis is complicated by the fact that the prescribed drugs must be not only effective, but also allowed during the gestation period. A distinctive feature of Pimafucin is that it is practically not absorbed into the blood, even when taken orally.

Medicinal properties of Pimafucin and release forms

The active component of Pimafucin is natamycin. This antibiotic belongs to macrolides, destroys most of the pathogenic fungal microflora. The most sensitive to its effects are the causative agents of candidiasis (Candida albicans). It can also be applied when fungal infection skin, the spread of yeast, representatives of the genus Penicillium and Aspergillus. The principle of action of Pimafucin is to destroy the cell membranes of infectious agents, as a result of which they die.

Important distinguishing feature Pimafucin is that it acts locally. The drug does not enter the blood, even if used in the form of tablets. This specificity makes it safe for use during pregnancy, breastfeeding, as well as for the treatment of children of different ages.

Pharmacies present 3 forms of Pimafucin:

1. Pills. Covered with a white shell, which is resistant to the effects of stomach enzymes and dissolves in the intestine. This allows you to effectively use the drug in case of fungal infection of the lower sections. digestive tract. The active ingredient is natamycin, auxiliary are presented potato starch, beeswax, sucrose, lactose, gelatin, talc, kaolin and some other compounds. Tablets are available in glass bottles of 20 pcs. The cost is 450-500 rubles.
2. Cream. White or yellowish color applied to damaged areas of the skin and mucous membranes. Natamycin is also present as an active substance, oleic acid ester and decyl alcohol, cetyl stearyl alcohol, wax, water and some other substances as auxiliary substances. The cream is available in tubes of 30 gr. The cost is 270-300 rubles.
3. Vaginal suppositories. Standard torpedo-shaped candles white color with yellow or brown tint. They are applied topically to eliminate infection on the vaginal mucosa. After the introduction, under the action of temperature, they dissolve and are distributed over the entire surface. The active substance is natamycin. Additionally, solid fat, cetyl alcohol, sorbitol and other components are present. Pimafucin suppositories during pregnancy are prescribed most often, since it is this form that copes with vaginal candidiasis more effectively than all the others.

Indications and contraindications

Pimafucin during pregnancy is indicated for diseases caused by the reproduction of pathogenic fungi. Most often, it is prescribed for acute vaginal candidiasis, since the disease easily occurs against the background of a natural decrease in immunity during this period. Also, its use is justified for fungal infections of the middle and outer ear, skin and mucous membranes. The infection can spread to the mouth, intestines, esophagus, eyes, and nipples.

Due to the fact that Pimfucin is not absorbed into the bloodstream, it has practically no contraindications. The only thing that can serve as a reason for refusing to use it or canceling it is individual intolerance to natamycin. In this case, the doctor replaces the drug.

Can Pimafucin be used during pregnancy?

To the question of whether Pimafucin is possible during pregnancy, the answer is given in the instructions for the drug. It is approved for treatment during this period, as well as during breastfeeding. Neither the fetus nor the newborn child negative impact will not be provided.

Pimafucin in the first trimester

In the first trimester, all doctors try to avoid prescribing any drugs and, if possible, focus on folk methods treatment. For infections without medications not enough. Safer are those that act locally, without penetrating into the bloodstream.

Pimafucin in the 1st trimester of pregnancy is most often prescribed for the treatment of thrush. Even the fact that the placenta has not yet formed, and all substances absorbed into the mother's blood enter the child, is not an obstacle to its use.

Pimafucin in the second trimester

During pregnancy, the 2nd trimester is considered the most prosperous. During this period, the list of permitted drugs is quite wide. Naturally, Pimafucin is included in it.

In the middle of pregnancy, the drug will be prescribed not only in the form of suppositories or cream, but also in tablets. With severe symptoms of candidiasis, the doctor may decide to take a more potent agent, since the placenta is already formed and partially protects the baby from harmful substances.

Pimafucin in the third trimester

Pimafucin during pregnancy in the 3rd trimester is most often prescribed for mild to moderate thrush. In severe manifestations, the drug is replaced by others (Viferon, Gino-Pervaril, Terzhinan).

On later dates a doctor may prescribe a course of Pimafatsunia for prophylactic purposes, especially if the infection manifested itself during pregnancy. This will prevent the risk of infection of the child during childbirth and help avoid complications associated with dryness and cracks in the vaginal mucosa.

Instruction and dosage

According to the instructions, Pimafucin can be used at any stage of pregnancy.

The choice of the form of the drug and the dosage depend on the disease and its severity.:

• Pimafucin tablets during pregnancy are prescribed to eliminate a fungal infection in the intestines, as well as in the chronic course of candidiasis of the skin and mucous membranes. The standard dosage is 1 tablet 4 times a day. The course of therapy usually lasts a week.
• Pimafucin cream (ointment) during pregnancy is prescribed for external use. With fungal infections of the skin and nails, it should be applied to the affected areas from 1 to 4 times a day. The same frequency of application is necessary for the treatment of mycosis of the external auditory canal, but after using the cream, it is necessary to introduce a turunda made of cotton or wool into it ( natural materials). The cream can be used to eliminate vulvitis, vulvovaginitis. The method of application is the same: apply thin layer on the affected area 1 to 4 times a day. The duration of treatment is set individually, the drug in this form must be used for a few more days after the symptoms disappear.
• Candles Pimafucin, according to the instructions, during pregnancy can be used at any time for the treatment of vaginal candidiasis, vulvitis and vulvovaginitis. Dosage - 1 suppository per day. The drug should be administered at night, in the supine position. The duration of therapy is determined individually, but on average it is 5-7 days. If the disease occurs in a chronic form, then tablets are prescribed along with the use of suppositories. The discharge after Pimafucin during pregnancy is due to the fact that the candle dissolves in the vagina and gradually leaves during the day.

Despite the relative safety of Pimafucin, during pregnancy it can only be used as directed by a doctor. The specialist will be able to assess the degree of the disease, as well as establish the optimal dosage of the drug and the duration of its use.

Side effects

Pimafucin in the form of tablets can provoke nausea and vomiting in the first days of admission, later these symptoms disappear. Suppositories and cream in some cases cause side reactions of a local nature: redness, itching, burning of the treated areas.

Rarely may appear allergic reactions. As a rule, the drug is well tolerated by patients of different ages, as well as pregnant women. Overdose increases the risk of side effects.

Under certain circumstances, it may be necessary to replace Pimafucin with other drugs. This medicine has analogues - products with the same composition and functions. The doctor may prescribe the use of Funzol, Funginok, Tsiskan, Fungavista.

The question often arises as to which is safer and more effective during pregnancy: Terzhinan or Pimafucin? It is important to know that these funds are not analogues, that is, they do not replace each other. Terzhinan has another active substance, and it can be administered in combination with Pimafucin. However, this drug is not recommended in the 1st trimester, and in subsequent trimesters it is allowed to use it as prescribed by a doctor.

Pimafucin during pregnancy is one of the most safe drugs for the treatment of candidiasis. It is not absorbed into the blood and therefore Pimafucin can be prescribed even for early dates pregnancy.

especially for Mama66.ru

After conception, immune functions decrease. This leads to the growth of pathogenic microorganisms. Many expectant mothers are familiar with fungal infections. The fungus can affect the dermis and mucous membranes. Diseases cause discomfort, the symptoms of thrush are especially unpleasant. Treatment of fungal infections in an "interesting" position is complicated by the fact that many drugs become taboo. But there are also such pharmaceuticals that will help get rid of the fungus and will not harm the baby. Doctors recommend using Pimafucin during pregnancy, the 1st trimester is not even a contraindication for the use of this drug.

When carrying out, you must follow all medical recommendations.

The main component of Pimafucin is the antibiotic natamycin. Thanks to him, the antifungal agent received the widest spectrum of action. Natamycin is able to destroy various pathogenic fungi, but candida (thrush pathogens) are the most sensitive to the substance. The drug effectively fights against pathogenic fungal microflora that provokes damage to the dermis.

Pimafucin destroys pathogens at the level of cell membranes. The peculiarity of the drug lies in the local action. The agent does not enter the blood fluid, in whatever form it is used (even in tablets). This drug- one of the safest among those created for the treatment of fungal infections.

Release form

Pimafucin is available in three forms. Which type of medicine is best suited for a particular clinical case, the doctor decides.

• Pills. Sold in glass bottles. Packaging - 20 pieces. The pills are coated with a special coating. It dissolves, getting into the intestines, gastric enzymes do not act on the shell. Given this property, the tablet form of the remedy is often used to eliminate fungal infections that have affected the lower gastrointestinal tract. Except active ingredient(natamycin), pills contain other substances: starch, lactose, sucrose.
• Cream. Available in tubes of thirty grams. A whitish or yellowish creamy agent can be used on damaged skin, mucous membranes. The main substance is similar to the tablet form, the main auxiliary ones are decyl alcohol, oleic acid (in the form of an ester), wax. After successful elimination vaginal candidiasis cream must first be used by a partner. This will avoid relapse.
• Vaginal suppositories. Under this concept, ordinary candles are hidden. They are torpedo-shaped. Method of application - topically. Used to eliminate a fungal infection on the vaginal mucosa. Candles are administered vaginally, where they dissolve under the influence of body temperature, after which the drug spreads over the surface of the vagina. The basis of suppositories is unchanged natamycin. In this form, the drug is most suitable for eliminating candida actively multiplying in the vagina. Candles effectively fight pathogens, leaving no chance for microorganisms.

Indications for use

The drug is prescribed for diseases that have developed as a result of the reproduction of fungi. The tool is indicated for use in:

• vaginal candidiasis (thrush);
• gastric candidiasis;
• fungal diseases of the gastrointestinal tract;
• ear mycosis;
• fungal infections of the skin, nails, oral mucosa, eyes.

Most often, the tool is used in the treatment of thrush. It really effectively fights candida, quickly relieves symptoms ( severe itching, palpable burning sensation).

Contraindications

The medicine can be used by anyone who is familiar with a fungal infection. The remedy has no contraindications, and all because the active substance does not enter the blood fluid, does not affect the tissues. That is, the action of the drug is directed exclusively to the fungal microflora: natamycin (the main component of the drug) does not affect organs and systems.

The only point that is important to consider is the individual intolerance of the substances included in the drug. It is important to study the composition of the pharmaceutical product before taking it and still consult a doctor. Then there will be no problems.

The expectant mother needs to get enough sleep.

Pimafucin and pregnancy

Expectant mothers are often diagnosed with thrush. From the moment of conception, the restructuring of the body begins, which leads to a decrease in immune responses. This is the impetus for the active reproduction of candida. When there are too many pathogenic microorganisms, thrush is diagnosed. The disease is accompanied by a pronounced clinical picture:

• severe itching;
• intolerable burning sensation;
• swelling of the vagina;
• painful urination;
• discomfort during intercourse;
• thick (curdled) white discharge.

A fungal disease must be treated: it causes discomfort to the expectant mother. The infection can be transmitted to the baby at the time of its passage through the birth canal. Pimafucin during pregnancy will help to cope with candidiasis. It is this drug that is most often prescribed by gynecologists to expectant mothers to fight fungi. The agent, as indicated by the instructions and clinical studies, does not enter the blood system. Due to this, the drug is recognized as completely safe.

The tool is also recommended by dermatologists, if fungal infection struck skin future mother. If necessary, the drug will help immediately after childbirth: the use of the drug does not interfere breast-feeding. The active substances act exclusively on the fungus, they do not enter the milk, which means they are not afraid of the baby. The drug is so safe that they even treat newborns if a fungal infection has occurred.

Features of application by trimesters

The active components of the drug are not able to penetrate the uteroplacental (protective) barrier. The drug is completely safe and will definitely not affect the fetus, whatever the gestation period.

A blood test will help to identify the pathology in time

However, despite the safety of the product, you need to visit a doctor before using it. Only a specialist can make an accurate diagnosis. It is important to determine the need for therapy in a particular week. Sometimes thrush is not treated immediately, but its course is monitored and only after that the therapy is selected.

Candidiasis tends to recur, so the treatment regimen should be chosen so that this does not happen. Treatment is holistic:

• relieve symptoms;
• prevent the development of a fungal infection;
• enhance immune functions.

In a word, only with the help of a doctor you can deal with all the nuances. The uncontrolled use of Pimafucin, although it cannot lead to complications and does not harm the baby, but if the treatment is incorrect, the symptoms will go away for a while, and later they will remind of themselves.

First

Fungal infections most often make themselves felt in the 1st trimester of pregnancy. After conception, a natural mechanism for reducing immune responses is launched. This is necessary to prevent rejection of the fetus. But the weakening of the protective functions entails the development of various diseases. The expectant mother becomes vulnerable to infections. Weakened the immune system cannot restrain the development of pathogenic microorganisms, resulting in thrush.

At the beginning of gestation, doctors do not recommend the use of pharmaceuticals. In the treatment of any ailments, the emphasis is on safe folk technique. The placenta is forming, and until it ends, the baby will be unprotected. But Pimafucin can be used in the first trimester of pregnancy. The agent does not penetrate into the bloodstream, which means that its active substances are not transported to the baby.

To be safe, Pimafucin in the 1st trimester is not prescribed immediately after the detection of a fungal infection, but at the ninth gestational week. Although if the symptoms cause severe discomfort to the patient, then the use may be allowed earlier: the drug will not cause harm to the embryo.

Any drugs in the initial gestational period should be discussed with your doctor. Pimafucin suppositories are usually prescribed during pregnancy, 1 trimester - dangerous time, tablet forms still need to be treated with caution.

Second

During pregnancy, the 2nd trimester, women are looking forward to. This so-called Golden time". Mom got used to the new status, toxicosis went away, strength and mood appeared. But long awaited months can be overshadowed by a fungal infection. Weakened by hormonal changes, the body cannot resist the pathogenic microflora. It begins to spread, and in the middle of the term makes itself felt.

By using special cream stretch marks can be prevented

The peculiarity of the second trimester lies in the wide possibilities of treating fungal diseases. The formed placenta provides the baby with protection, so you can not be afraid to accidentally harm a new life. The choice of drugs depends largely on clinical picture. If the symptoms of candidiasis are not very pronounced, then Pimafucin is used during pregnancy, the 2nd trimester allows you to use the medication in any format (cream, pills, suppositories). Candles are usually prescribed at the first appearance of signs of candidiasis, pills - with pronounced symptoms.

If the disease progresses rapidly and treatment with Pimafucin is not enough, then the doctor, having assessed the risks, may suggest replacing a safe remedy with potent medications. Self-administration of such medicines is prohibited. Mom cannot adequately assess the consequences of the use of antifungal agents. Negligence can lead to the development of intrauterine anomalies in crumbs.

Third

Thanks to a special active ingredient, it is always safe to use Pimafucin suppositories during pregnancy, the 3rd trimester is no exception. On recent months You can buy the product in creamy form, in tablet form. The doctor will select the type of pharmaceutical preparation: this is the only way to achieve a result.

Pimafucin during pregnancy in the 3rd trimester is usually prescribed for initial stage fungal disease. The tool will help relieve signs of candidiasis of moderate severity. If the disease is advanced, the manifestations cause severe discomfort to the patient, then the gynecologist may recommend other drugs - with maximum effect. In the third period of gestation, the baby is fully formed, the small organism is protected by the placenta, which makes it possible to "turn around" in terms of treatment. If in the first weeks they always prefer Pimafucin, as the most safe means, then on the latter - the choice is wide. Many antifungal drugs that were previously banned are no longer taboo before childbirth. But choosing medicines is the competence of a doctor, not a mother.

The course of Pimafucin closer to childbirth is sometimes prescribed for prevention purposes. Preventive measures are relevant for those patients in whom the infection manifested itself in nine months (no matter what period of gestation). With a prophylactic course, candles are used. Candidiasis may be undertreated and not give itself away. This measure will help to avoid infection of the crumbs in the process. labor activity. Additionally, suppositories help eliminate vaginal dryness, promote healing of cracks in the mucous membrane. Before childbirth, getting rid of such problems is extremely important.

Instruction and dosage

Although the remedy can be safely used to treat fungal infections while waiting for the baby, however, the use should be preceded by a trip to the obstetrician-gynecologist. The dosages recommended by the manufacturer are one thing, but the recommendations of a specialist are completely different.

If you feel unwell, you should not self-medicate

The instructions for the preparations indicate generalized doses, for each specific case The therapeutic scheme should be selected individually. The doctor determines in what form the drug is best used, sets the dose based on the clinical picture, the degree of development of the disease.

• pills. Pimafucin tablets during pregnancy are prescribed if the fungus is activated in the intestines, candidiasis on the mucous membranes / dermis has become chronic. The standard scheme is considered to be one pill four times a day. The course usually lasts seven days.
• Cream. Application depends on the site of the lesion and the degree of spread of the infection. If the fungus has occupied the skin, the nails are affected, then the affected areas should be treated up to four times a day. With a slight lesion - once is enough. A similar algorithm for vulvovaginitis. Ear mycosis requires treatment up to four times, but after applying the cream, it is necessary to insert a turunda made of natural materials into the ear canal. The duration of therapy with the external form of the drug is determined individually, but after the symptoms disappear, the treatment of previously affected areas continues for several more days. This leaves no chance for pathogens.
• Candles. Usually appoint one suppository per day. The procedure is done at night. By morning, the candle dissolves and gradually comes out. This provokes specific discharge. On average, the procedures are delayed for a week. Chronic form infection requires supplementation treatment regimen: a tablet form of the drug is added to the suppositories.

The duration of the course should be determined by the doctor. Having started treatment, it is necessary to adhere to the planned scheme. If you refuse the drug, arbitrarily reduce the dosage, then there is no need to wait for the effect. Any changes during the treatment period should be announced to the doctor: this is important for understanding the clinical picture and subsequent adjustment of therapy.

Side effects

When using Pimafucin side effects rarely occur. However, no one is immune from them. What to expect?

• Tablets can provoke vomiting, cause nausea, diarrhea. When administered before the middle of gestation, pills can increase the manifestations of toxicosis. Usually "side effects" disappear two days after the start of treatment.
• From the cream, suppositories, local reactions may appear. The treated area may itch, and there may be a burning sensation. If the discomfort is strong, then an allergic reaction has gone. Usually with allergies in addition to unpleasant sensations there is a rash, redness of the dermis.

The initial reaction to the drug does not require any treatment. The side effects usually go away on their own. next day after the start of therapy. But you need to tell your doctor about them. If an allergy has begun to the components of the drug, stop taking it and look for alternative solutions Problems.

You can and should include nuts and seeds in your diet.

Allergic manifestations, pronounced side effects often appear when the dosage is not observed. The drug should be used strictly according to the prescribed scheme and do not arbitrarily increase the dose.

Analogues

During the period of bearing crumbs, Pimafucin is optimal for eliminating a fungal infection. Efficiency and complete safety are the main advantages of the drug. It is these criteria that are important in the treatment of expectant mothers.

However, it happens that the remedy for some reason is not suitable. Then select analogues. It is important that they are as harmless as possible for the crumbs. Substitutes should not be looked for on your own: they should be selected by a specialist. by the most known analogues are:

• Ciscan;
• Funzol;
• Fungavista;
• Funginok.

Many mistakenly consider Terzhinan to be an analogue of Pimafucin. However, they have different active substances: these two drugs cannot replace each other. But they are perfectly combined, so the drugs are often prescribed in tandem. Terzhinan can be used in addition to one of the forms of Pimafucin only if prescribed by a doctor. This drug, unlike natamycin-based products, cannot be used in early gestational periods.

Prevention of fungal infections

Ideally, fungal vaginal infections should be treated before conception. But far from all families are planning a baby responsibly. And with careful planning, no one is insured that thrush will not suddenly manifest itself or future mommy will not be infected by a fungus that affects nail plate or skin. Therefore, prevention should always come first. Simple Rules help to avoid any diseases provoked by pathogenic fungi:

• Proper care intimate area. By washing twice a day using a special gel, you can avoid thrush.
• Choice in favor of cotton linen. Under synthetics, the dermis does not breathe, candida begins to actively multiply.
• Frequent change panty liners. Pads should be changed at least three times a day.
• Diet change. Refined foods rich in carbohydrates, sugar create an optimal microflora in the intestines for the activation of yeast-like microorganisms. The diet should include as many bifidoproducts as possible.
• strengthening immune functions. Good rest, vitamins, walks, moderate activity - this is how defense mechanisms organism.
• Personal caution. You can not use one towel, walk barefoot in public places - you can catch a fungus.
• Wise use of medications. Unauthorized medication disrupts the intestinal microflora, opening the way for fungal infections. But the main thing is that careless actions can harm the crumbs.

In an “interesting” position, it is extremely important to quickly read the signals that the body gives, and respond to them in a timely manner. The sooner a fungal infection is detected, the higher the chances that it can be eliminated before the baby is born. This means that infection of the crumbs will not occur. Treatment of fungal infections in expectant mothers should be carried out exclusively under the supervision of a doctor and using only safe drugs.

Pimafucin is a truly invaluable drug in the treatment of various fungal infections of the skin and mucous membranes. The drug belongs to the antifungal polyene antibiotic a wide range actions. The medicine is prescribed for various types, and with otomycosis, and with external otitis caused by fungi, and with candidiasis of the skin, nails, intestines, vagina. Often doctors, in the absence of other such harmless drugs, similar diseases prescribe during pregnancy the reception of this particular drug. After all, the use of Pimafucin is allowed at all stages of pregnancy and during lactation. At least, because there are no data on adverse effects on the fetus.

Pimafucin is produced in three dosage forms. These can be coated tablets, usually 20 pieces per pack. It can be - suppositories - vaginal - usually three pieces per pack. Pimafucin is also produced in a cream for external use 2%, 30 g each in a tube. And pimafucin is also produced in the form of a suspension for local application 2.5% - in 20 ml bottles complete with a pipette.

One tablet or one Pimafucin suppository contains 100 mg of natamycin. In one gram of cream - 20 mg of natamycin, and in 1 ml of suspension Pimafucin - 25 mg.

As you might have guessed from the composition of the drug, the active ingredient in Pimafucin is natamycin. It's all about the mechanism of its action - natamycin. It binds sterols of cell membranes, disrupting their integrity and function, and leads to the death of harmful microorganisms. Therefore, natamycin is not actually absorbed from gastrointestinal tract from the surface of the skin and mucous membranes. If the drug is taken in tablets, then it acts only in the intestines.

Doses of the drug are prescribed by the doctor, he also considers the most appropriate form of release for the pregnant woman. For a future mother, as a rule, the best option- these are candles, but there are cases when the drug is prescribed in other dosage forms.

The most common disease in which Pimafucin is prescribed during pregnancy is. This is due to the fact that a woman experiences a change during pregnancy. hormonal background. The immune system of the expectant mother is greatly weakened, the natural defenses of the body, respectively, are reduced, and therefore violations of the normal bacterial flora often occur.

Side effects that may occur with the use of Pimafucin are nausea, diarrhea (especially often occur in the first days of admission, as treatment progresses quickly).

As for skin irritations, they are also possible. Burning is also possible.

If the disease is chronic or advanced, then Pimafucin cream can also be prescribed for use, for example, tablets. Ban on sexual life doctors do not put (unless, if there are any contraindications associated with the course of pregnancy), but it is very desirable to conduct full examination sexual partners. If the husband also has an infection, then he will have to undergo treatment. At the same time, it is very desirable to use barrier contraceptives during sexual intercourse.

Especially for- Maria Dulina

From Guest

I also treated thrush with pimafucin, it helped, the thrush never returned.

From Guest

I treated thrush during pregnancy, since nothing was possible, they treated me with pimafucin. It helped well, the thrush passed and did not return.

During pregnancy, chronic diseases are often exacerbated or diseases appear that have not bothered until that time. The fungus can cause discomfort, as well as affect the well-being of the mother and the health of the unborn baby. Will Pimafucin help in this case and is it safe?

Is Pimafucin harmful during pregnancy

Pimafucin is a topical antibiotic that is indicated for the treatment of fungal diseases of the mucous membranes and skin. According to the instructions, this drug can be used during pregnancy. It is indicated that there are no data on the effect on the fetus. Most often, expectant mothers are prescribed this medicine for thrush, or candidiasis.

Of course, no clinical trials of drugs for pregnant women are carried out, but this drug is considered one of the safest.

Pimafucin can be prescribed by a doctor even in early pregnancy. In the first trimester fungal diseases women are potentially dangerous for the unborn child: there is a possibility of miscarriage or miscarriage. In the II and III trimesters, the infection is fraught with intrauterine infection fetus. Also, during childbirth, the baby can become infected with a fungal disease. Therefore, throughout pregnancy, it is important to listen to your condition and start treatment on time if necessary. However, there is another medical opinion.

Thrush is considered physiological norm pregnancy, as increased growth of the fungus is observed in 80-90% of pregnant women. It is not dangerous for both the pregnant woman and the fetus and newborn.

E.P. Berezovskaya
http://www.komarovskiy.net/faq/beremennost-i-molochnica.html

Composition, action and form of release

The active ingredient in Pimafucin is the antibiotic natamycin. It acts only locally and is not absorbed into the blood. Its content varies depending on the form of release of the drug.

Pimafucin is available in suppositories, tablets and in the form of a cream. With thrush, vaginal suppositories are most often prescribed. If the focus of infection is in the intestines, then the doctor can supplement the treatment regimen with taking pills. Cream in similar cases It is used when a fungus affects the external genital organs of a woman and her sexual partner.

Photo gallery: Pimafucin release forms

Pimafucin tablets are intended for oral administration with intestinal candidiasis Pimafucin cream has a local antifungal effect on the skin and mucous membranes Pimafucin vaginal suppositories are most often prescribed for thrush

What helps: thrush, colpitis and other indications

In most cases, during pregnancy, vaginal candidiasis is treated with Pimafucin, however, the range of application of this local antibiotic is wide, which allows it to be successfully used for other fungal infections. Indications are slightly different for different forms of release of the drug.

Tablets can be prescribed for:

• acute pseudomembranous and atrophic candidiasis;
• otomycosis, external, caused by fungi or complicated by candidiasis;
• skin and nail candidiasis;
• intestinal candidiasis;
• vaginitis (colpitis), vulvitis, vulvovaginitis, balanoposthitis;
• dermatomycosis.

Suppositories are successfully used from:

• vaginitis ();
• vulvitis;
• vulvovaginitis.

The cream can be prescribed in case of:

• vulvitis;
• vulvovaginitis;
• balanoposthitis;
• skin and nail candidiasis;
• otitis externa with candidiasis;
• dermatomycosis.

Despite the safety of the drug, you should not self-medicate. Only a doctor can determine the exact diagnosis and choose suitable shape medications and individual therapy regimen.

Instructions for safe use

Features of the use of candles, tablets and cream

According to the instructions, Pimafucin in candles should be used 1 time per day for 3-6 days. The suppository should be administered at night in the supine position. This is necessary so that the medicine released when the candle melts does not leak out.

The drug in tablets is prescribed 4 times a day. The course usually lasts no more than 1 week. Treatment with tablets can be combined with the use of suppositories and creams.

Usually, after the disappearance of unpleasant symptoms, Pimafucin therapy is continued for several more days to prevent a recurrence of the infection.

The final duration of the course of treatment for all forms of the drug is set by the doctor individually, taking into account the patient's condition.

Contraindications and side effects

Among the direct contraindications in the instructions for Pimafucin, only hypersensitivity to natamycin and auxiliary components of the drug. Local side effects - vaginal irritation and burning sensation - may appear when using Pimafucin in suppositories or in the form of a cream. They are short-term and usually do not require discontinuation of the drug. Tablets have a wider range side effects:

• nausea,
• diarrhea,

Individual reactions associated with intolerance to the components of the drug are possible.

The active substance natamycin does not penetrate the placenta and into the bloodstream that connects the body of the mother and child. Therefore, Pimafucin is considered safe during pregnancy. If any serious side effect still occurs in a woman, then treatment should be stopped, since it is likely that a similar negative effect can happen to the fetus. For example, if a mother has an allergy, then the baby may be born with a tendency to have the same reaction.

What can replace Pimafucin in different trimesters of pregnancy

It also happens that Pimafucin does not help to cope with fungal diseases that bring severe discomfort. Some women note that after a course of treatment with this drug, discharge and other unpleasant symptoms continue to bother them. In this case, it is necessary to consult a doctor and choose another drug that is safe during pregnancy.

Table: Pimafucin analogues, clotrimazole and other antibiotics for the treatment of fungal diseases at different stages of pregnancy

Photo gallery: drugs prescribed for pregnant women with fungal infections

Polygynax is not recommended for use in the first trimester of pregnancy. According to the manufacturer, Nystatin can be taken during pregnancy vaginal tablets Terzhinan can cause mucosal irritation and allergic reactions.
In the first trimester of pregnancy, clotrimazole is not recommended for use. Candide-B6 is not prohibited during pregnancy, but the benefit to the mother and the risk to the fetus should be weighed
Primafungin is a pharmacological analogue of Pimafucin

It is not for nothing that thrush is portrayed in advertising ironically and even with some degree of anger - an annoying disease occurs at the most inopportune moment, and the symptoms are such that at least do not go out to people. Plus, a relapse if the therapy is carried out untimely or not very competently.

Pregnant women in the 1-2 trimesters are especially affected by candidiasis. As a rule, the disease most easily overtakes them - future mothers, who are practically deprived of reliable immunity.

It should be noted that candidiasis is actively manifested in pregnant women precisely in the early stages, creating an additional problem for both women and attending physicians: how and with what to treat the disease, if the use of drugs during pregnancy is undesirable, and, apart from medicines, there is no way to get rid of thrush and a number of others. fungal diseases.

"Companion", which is absolutely not needed

No matter how hard the expectant mother tries to avoid candidiasis, this is far from always possible, and a weakened immune system is the main reason pregnant women are susceptible to infectious diseases.

Serious violations of the microflora of the vagina become a consequence of a weakened immune system and create favorable conditions for the development of Candida fungi.

Is it possible to avoid a pregnant unpleasant fate and somehow prevent the disease? Preventive measures against candidiasis, women should carry out even before pregnancy, having comprehensively examined the body, and if hidden diseases of the genitourinary system are detected, cure them.

If prophylaxis must be carried out already during pregnancy, then a woman must adhere to certain rules:

• give up underwear made of synthetic materials;
• as often as possible, change, wash with high quality and iron linen made of natural "breathable" fabrics before putting on;
• do not wear tight-fitting things, give up thongs;
• in the heat, do not wear synthetic tights;
• do not walk in a wet swimsuit for a long time: take a spare set both to the beach and to the pool;
• observe intimate hygiene, do not get too carried away with very fragrant hygiene products with a chemical component;
• dry the genitals after bathing;
• wash from front to back (as well as wiping);
• before intimate hygiene wash your hands well, make sure that there is no contamination under the nails;
• abandon the douching procedure so as not to wash out the beneficial microflora;
• eat a balanced diet.

Candidiasis is dangerous and relatively safe

The clinical picture of candidiasis in each individual case has distinctive features: symptoms different forms thrush takes on a completely different look, and sometimes it is simply impossible to notice. And this is very dangerous, because the disease will develop anyway and its peak may fall on the most defenseless period of pregnancy - the first or second trimesters.

We propose to consider this not very attractive picture closer, in order to recognize candidiasis, if necessary, even if it wants to “encrypt”.

1. Form - carriage. Symptoms - absent, candidiasis can be diagnosed only during the examination after receiving a smear analysis.

   Treatment should begin immediately so that the disease is not transmitted to the newborn baby during childbirth.

2. Acute form of the disease. Symptoms:
   • constant burning sensation in the vagina, aggravated during urination, wearing too tight underwear, after taking a warm bath;
   • appearance thick discharge curdled type;
   • swelling and redness of the external genital organs;
   • pain when urinating.
3. Chronic form(persistent candidiasis). Symptoms are temporarily absent, and the woman may have the illusion of a complete recovery, but after a while the symptoms return. They are identical to the symptoms in the acute form of the disease.

   If the disease in this form is found in a woman in the 1-2 trimesters, then most likely the infection occurred long before pregnancy. Therefore, once again we focus your attention on the mandatory examination at the stage of pregnancy planning.

Pimafucin and sauerkraut

If fungi of the genus Candida are detected on the mucous membrane of a pregnant woman, the attending physician is obliged to immediately begin therapy, choosing the most optimal variant of the medication.

Pimafucin is traditionally considered the safest during pregnancy. And although innovative doctors now and then declare that the drug is outdated, this does not negate its effectiveness.

The presence of an antibiotic in the composition of the preparation is somewhat frightening for future mothers, but this is typical for medicines of the antifungal group - otherwise it will not be possible to get rid of the disease.

So that the presence of an antibiotic does not really bother women, many doctors (from conservatives) advise during the use of the drug to increase the number of dishes from sauerkraut and pickles in your diet (not pickled - just salted, knowing the fermentation process). The probiotics found in these foods help prevent urinary tract infections.

In addition, such food is very loved by pregnant women, especially in the first weeks, when they are drawn to sour. And in alliance with Pimafucin, sauerkraut works just fine.

Composition and pharmacokinetics of Pimafucin

The active substance of the drug is a broad-spectrum antibiotic natamycin.

Once in the body, it binds the particles of the membranes of negative cells, contributing to their destruction.

Natamycin is not absorbed into the bloodstream when using suppositories or cream, which means it is safe for the fetus. To get a result from the use of the drug, a woman needs to undergo a long course of treatment - Pimafucin is non-toxic and acts very slowly. This is what caused the fact that some modern doctors recognized the drug as obsolete.

Release the drug in the form of tablets, rectal suppositories, vaginal suppositories, creams for external use.

Dosage and duration of therapy

In the acute form of candidiasis, the doctor, except vaginal suppositories, appoints a pregnant woman also Pimafucin tablets.

Taking the medicine inside accelerates the process of destruction of Candida fungi in the intestines and improves the effect of exposure. But the question arises: how much does a pregnant woman risk when taking pills. After all, if the probability of absorption of the active substance of the drug from the mucous membranes is minimized, then through the walls of the stomach the antibiotic can enter the bloodstream, although pharmacokinetic studies of the drug prove the opposite.

In any case, when using Pimafucin in the form of tablets, care should be taken.

If the standard dosage of Pimafucin in the form of suppositories is one suppository per day, then the tablets should be prescribed by developing an individual schedule. The treatment course with the use of tablets is at least two weeks.

Pimafucin cream is applied to the affected area 1-2 times a day, the use of this form of medication is considered auxiliary. The course of treatment is prescribed by the doctor.

Side effects

Often the use of antifungal vaginal suppositories causes side effects that are very difficult to distinguish from the symptoms of the disease: the same burning sensation, the same pain sensation, the same redness.

If you notice such manifestations during therapy, be sure to tell your doctor about it and ask to change the drug.

Other side effects:

• nausea;
• allergic reactions;
• vomit;
• stool disorder.

Harmless means ineffective?

Let us return to the topic of a long course of treatment and the safety of the drug for the fetus and the pregnant woman. Harmlessness is often perceived as a synonym for inefficiency. Is this the case with Pimafucin, which some doctors have stopped prescribing for the duration of therapy and the fact that it does not help all women.

The opinions of specialists about this drug drastically differ, some doctors prescribe suppositories throughout the entire period of pregnancy, absolutely not fearing for the health of the mother and fetus, while others are guided by the nuances of the clinical picture and exercise caution when prescribing, others do not consider Pimafucin effective tool, and avoid its appointment for this very reason.

Pimafucin by trimester

1 trimester

Assign in the form of candles or cream. The course of treatment is 3-6 days, but depends on the neglect of the process. Apply at night, in the supine position. Most experts advise to undergo an examination on the eve of a planned pregnancy, cure all chronic diseases of the urogenital system and strengthen the immune system so that medications are not used in the early stages. It is undesirable to take Pimafucin tablets in the first three months of pregnancy.

2 trimester

In the second trimester, the use of suppositories and Pimafucin cream is allowed. Tablets are prescribed in case of urgent need.

3rd trimester

In the third trimester, it is possible to prescribe all forms of the drug.