Indications for use are. What is dangerous Ginipral during pregnancy: side effects, effects on the fetus

In the practice of an obstetrician-gynecologist, quite often one has to deal with the opinion that ginipral during pregnancy is prescribed almost at the whim of a doctor or just in case. Meanwhile, there are strict limits for the appointment of this drug and a number of contraindications for use.

What is ginipral?

Briefly about what this drug is and why they take ginipral during pregnancy. The drug belongs to the group of sympathomimetics, is a remedy for the treatment of hypertonicity and excessive contractile activity of the uterus. Widely used for prevention premature birth and treatment of increased uterine muscle tone.

The uterus is a muscular organ and, like other muscular formations, is able to contract. During a physiologically proceeding pregnancy, muscle fibers are in a relaxed state, contractions begin with the arrival of the term of delivery. Unfortunately, most women come to pregnancy unprepared, with a load of comorbidities, bad habits, sedentary lifestyle. There are many factors contributing to the development of hypertonicity of the pregnant uterus. This is a formidable sign, fraught with the threat of miscarriages and premature births, as well as - intrauterine hypoxia and retardation in fetal development. All this happens due to insufficient supply of oxygen and nutrients to the child. We use ginipral during pregnancy starting from the 20th week and have enough good performance gestation.

Side effects of taking ginipral during pregnancy!

Many women complain of heart palpitations, headaches, dizziness while taking the drug. I would like to draw attention to the fact that this does not affect the cardiac activity of the child. Such complaints usually disappear when the dose is reduced to 1 tablet per day. Also, to prevent complications from the cardiovascular system, drugs are prescribed that reduce the heart rate, and potassium supplements are taken in parallel. In some cases, it is sufficient to take valerian extract in tablets.

When taking ginipral, you should consume less salt and liquids to prevent possible edema. Tea and coffee aggravate unwanted effects ginipral.

When should ginipral not be taken during pregnancy?

Of particular note are the conditions when taking ginipral during pregnancy is undesirable or contraindicated:

Individual intolerance;

hyperfunction thyroid gland;

Diseases of the heart and blood vessels, including cardiac arrhythmias with rapid heart rate, hypertension.

Uterine bleeding;

First trimester of pregnancy.

It would not be superfluous to recall that treatment with ginipral is started only as directed by a gynecologist. When taking the drug, daily measurement of blood pressure and heart rate is mandatory, with diabetes mellitus - strict control of glycemia (hyperglycemic conditions are possible). Ideally, when taking ginipral, CTG should be performed daily to clarify the condition of the fetus and the tone of the uterus. In real conditions, such studies are carried out depending on the technical capabilities of a particular medical institution.

None of the experts will be able to give a 100% guarantee that even a pre-planned pregnancy will proceed systematically and according to the norm. Unfortunately, even careful to such a responsible step as carrying a baby is not able to guarantee future mother from any, albeit the most insignificant complications of a joyful period. What can we say if pregnancy overtakes a woman unprepared! In this case, the risk of encountering unforeseen complications increases, and therefore it is necessary to do everything possible to avoid these complications.

One of them is increased, hypertonicity. Many factors can become a catalyst for the development of such a condition - when the muscles of the uterus contract too often or are constantly in a tense state. This formidable state is dangerous with unforeseen and complex consequences - up to spontaneous abortion or more later dates pregnancy.

Ginipral during pregnancy: instruction

When diagnosing, specialists are forced to resort to all kinds of drugs to relieve her stress. In this case, one cannot do without drugs: an increased tone of the uterus can not only lead to a miscarriage, but also “slows down” the supply of nutrients and oxygen to the fetus, which causes and slows down normal development baby. If in the early stages of pregnancy, more and more hormonal drugs are used to relax the uterus (hypertonicity during this period is more often associated with impaired hormone synthesis), then closer to the second half of pregnancy, doctors prefer more serious drugs. One of them can be Ginipral, a drug that has a direct effect on the vessels of the uterus and placenta, thereby contributing to its relaxation. Ginipral during pregnancy can be prescribed no earlier than 16-20 weeks: the first trimester is a contraindication to its appointment. To decide whether there is a need to use Ginipral, only a doctor can determine, he also sets the dosage and duration of the medication. Ginipral during pregnancy can be prescribed both in the form of tablets and in the form of injections: in this case, it is administered intravenously through a dropper.

Contraindications to taking the drug are individual intolerance to its components, hyperfunction of the thyroid gland, bronchial asthma, diseases of the heart, kidneys and liver, glaucoma. But even if there are no contraindications for choosing the drug Ginipral during pregnancy, taking it can still often be accompanied by side effects. Among them, the most common are palpitations, headaches and dizziness, agitation, trembling of the limbs. To prevent or to eliminate unpleasant consequences from taking Ginipral, in parallel with it, drugs that reduce cardiac activity are prescribed, and also often potassium preparations. Since taking Ginipral can also cause sudden pressure surges and an increase in blood sugar, drug therapy should be accompanied by constant monitoring of blood pressure, heart rate and sugar. It will not be superfluous for a pregnant woman to limit the intake of salt and liquid, in order to avoid edema; be wary of tea and coffee, which can enhance the undesirable effects of Ginipral.

Ginipral during pregnancy: dosage

It should be remembered that it is by no means possible to prescribe arbitrarily or independently cancel Ginipral during pregnancy. The need for drug therapy, as well as its dosage, is determined solely by the doctor strictly individually.

In emergency cases, Ginipral is prescribed "complex": intravenously, and some time before the end of the dropper - in tablet form. In this case, a solution is prepared for intravenous administration: 50 μg (2 ampoules of 25 μg each) of the drug are diluted in 500 ml of a 5% glucose solution. 2-3 hours before the end of the dropper, you should start taking tablets - first 1, then after 3 hours, 1 tablet every 4-6 hours. Daily dose, thus, should be 4-6 tablets, the medicine is washed down with a small amount of water.

If there is no need for intravenous administration of the drug, Ginipral can be prescribed as a course (sometimes for several months) in the form of tablets. Satisfactory condition allows dosage from a quarter of a tablet to one whole (500 mcg) every 4-6 hours. At strong tone Ginipral can be prescribed at the rate of 1 tablet (500 mcg) every 3 hours. Achieving the effect in the form of a decrease in the tone of the uterus allows for a decrease in dosage - first, the time between doses increases to 4-6 hours, the dosage is gradually reached in the amount of 1-2 tablets per day.

Cancellation of the drug is carried out gradually, with a dose reduction at each dose. This is a necessity, especially if the drug therapy involved sufficiently high doses of Ginipral: with its abrupt cancellation threatening symptoms premature termination of pregnancy is resumed.

Especially for - Tatyana Argamakova

From Guest

I was injected with ginipral intravenously for 3 days in the hospital. I had to lie down for a long time, the first day was generally about 8 hours, but my condition improved instantly. The baby became much calmer and began to sleep more.

From Guest

They dripped only 2 days for 4 hours. There are no complaints about the drug, although it has its drawbacks. here already someone how to endure.

From Guest

I'm at 26-27 weeks. I don’t have a particular threat and there is no tone, and on the ultrasound they said there is no tone. But since I always have pre-temporary childbirth, doctors are afraid and prescribed this ginipral for me, first droppers 3 times a day dripped for 5 hours and then switched to 1/4 tablets 4 times a day. After eating every 4 hours. But side effects happens but tolerable. I advise everyone if the doctors have prescribed you, then drink the doctors know what they are doing. All health and more kids

From Guest

I have an intolerance to this drug. The whole arm turned red where they put the dropper, the pressure jumped, strong pain in the vertex of the head and dizziness. Doctors had to stop treatment with ginipral. Why inject if I didn’t have uterine tone?!

From Guest

Helps very well. I have 23 weeks, the tone of the uterus quickly removes no words. Drip 4 hours

From Guest

She tolerated droppers well if they dripped slowly. Once I asked my sister to speed up - my heartbeat became more frequent, but maybe I just knew about it side effects. The main thing after any dropper is not to get up abruptly - lie down for 15 minutes. For the sake of preserving pregnancy, you can endure everything - 4-5 hours of a dropper, this is a trifle, especially since the drug helps

From Guest

Ginipral was prescribed from 6.5 months to 1/4 4 times a day. The tone is gone. Then the dose was increased to 1.5 tablets per day. At 35 weeks, the tone began and contractions began. In the maternity hospital, they immediately put him on a drip for 6 hours with him. The contractions stopped going, the tummy relaxed. Yes, there are side effects: tremor, tachycardia, but the main thing is that it performs its function and the consequences without it are much worse than a side effect.

From Guest

And I ended up in the hospital at 30 weeks with terrible pain in right side belly, turned out uterine hypertonicity, I couldn’t even walk. I immediately put a dropper with ginipral, and started drinking pills for three days, only after that it got better, I continue to drink and now 3 tablets. a day. There were no side effects, although the nurse did not leave me and was constantly interested in my well-being.

From Guest

I drank ginipral 1/4 3 times a day, there were no side effects. Also, twice I was dripped with it intravenously for three days, there was a slight heartbeat, before the droppers I took Corvalol 30 drops. If ginipral is prescribed, then drink, do not exceed the dosage, if prescribed intravenously, then drip it very slowly, this will help you, if not completely avoid side effects, then at least reduce them for both you and the baby.

From Guest

34 weeks of pregnancy, the doctor prescribed ginipral. I'm afraid to drink it. There is a tone of the uterus, but I think it's normal for my period. All the same, the uterus is preparing for childbirth. I decided not to drink it.

From Guest

Ginipral was discharged at 27 weeks. took 3 days, as the doctor said, a tablet on demand, it turned out 1t, 1r / d ... I announce the list of side effects that appeared: swelling of the legs, difficult diuresis, nausea-vomiting, tremor of the fingers, increased sweating, and now I enjoy coughing, in the instructions it is indicated that cough is a symptom of pulmonary edema, I think to call a joint venture or still live until the morning before the clinic ... unfortunately, the instructions do not say, except for cancellation, to do with a full set of side effects. But in general, the drug fulfills its purpose, uterine contractions go well for a fairly long time.

From Guest

Also, from about the 25th week, the stomach began to periodically turn to stone, but this did not bother me, because. There was no pain and passed in 10-20 seconds. However, then it became more frequent, even in a calm state, the doctor prescribed Ginipral 1/4 4 times a day, but nothing has changed - everything also happens to tone several times a day. I don't know if it helps at all.

At the beginning of pregnancy, it is impossible to predict how these nine months will proceed. And even planning proper nutrition And medical examinations are not a guarantee of the absence of complications. One of the most common is the tone of the uterus. In the early stages, this condition can lead to miscarriage, and in the later stages, to premature birth. To relieve muscle tension, doctors may recommend Ginipral.

Why is Ginipral prescribed during pregnancy

The female uterus is the organ in which it grows and develops new life- consists of muscle tissue. At normal flow pregnancy, it is in a relaxed state and increases as the fetus grows. However, in some situations, the muscles begin to contract constantly or periodically. This condition is called uterine tone. It can be caused by several reasons:

• bad habits during pregnancy;
• wrong lifestyle (lack of walks, poor or insufficient sleep);
• nervous strain and stress;
• malformations of the fetus, adenomyosis of the uterus, fibroids, diseases endocrine system;
• genetic predisposition.

Cramping or pulling pains in the uterus or back, tension and "petrification" of the abdomen may be signs of increased tone. When they appear, you need to seek advice from an obstetrician-gynecologist.

The tone of the uterus is a dangerous condition in which a woman should be under the supervision of specialists. If you do not correct it in time, serious consequences and complications of pregnancy are possible:

• hypoxia (because nutrients and oxygen does not reach the fetus in full);
• miscarriage or premature birth.

Ginipral is prescribed in cases where, without drug treatment not enough. It helps to relieve muscle tension in the uterus due to the properties of the active substance - hexoprenaline. The drug is used if necessary:

• decrease in tone at the risk of premature birth;
• braking labor activity with a complicated course of childbirth;
• relaxation of the uterus before a caesarean section.

According to the instructions, Ginipral is contraindicated in the first trimester. More often, doctors recommend taking it after the 20th week, but in case of a threatened abortion, the drug can be prescribed from 16–18 weeks.

Ginipral cannot be taken on its own: only after a thorough examination and diagnosis, the doctor decides how justified the use of the drug is.

Release form: tablets and solution for intravenous administration through a dropper

Ginipral is available in two forms: tablets and concentrate for the preparation of a solution for intravenous infusion. Tablets are more often prescribed with a small threat of abortion, as well as for the prevention of uterine tone. To provide emergency assistance the drug is administered intravenously through a dropper.

Dosage and maximum duration of administration are determined individually. It depends on the characteristics of the course of pregnancy, the degree of risk of preterm birth and the development of the fetus. In some cases, a monthly course of treatment is sufficient, in others, women are forced to take Ginipral throughout the second half of pregnancy.

How to cancel Ginipral during pregnancy

Ginipral should not be stopped abruptly. Waiver of it occurs gradually by reducing the dosage. Otherwise, the symptoms quickly return and the risk of miscarriage arises again. In obstetric practice, the drug begins to be canceled at 35-37 weeks. The use of the drug after this period inhibits labor activity and may require labor induction.

Contraindications and side effects

Ginipral should not be taken in the following cases:

• diseases of the endocrine system (hypertrophy and hyperfunction of the thyroid gland);
• premature detachment of the placenta, uterine bleeding;
• diseases of the cardiovascular system (, tachycardia, arrhythmia, myocarditis);
• diseases of the liver and kidneys;
• closed;
• intrauterine infections;
• individual sensitivity to the components of the composition.

During the use of the drug, side effects may occur:

• and dizziness;
• increased blood sugar levels;
• decline blood pressure;
• edema;
• increased heart rate;
• sleep disturbance and trembling in the hands;
• decreased intestinal tone and constipation.

Side effects can also be noted in a child after childbirth: hypoglycemia, acidosis, bronchospasm, anaphylactic shock.

How to replace Ginipral

Ginipral is replaced with another drug if there are contraindications or severe adverse reactions, as well as in the case when tension in the muscles of the uterus is observed in the first trimester of pregnancy.

Comparative characteristics of drugs that have a similar effect to Ginipral - table

By different reasons Pregnancy doesn't always go well. The tone of the uterus is familiar to many women in position, but sometimes there are more serious situations that really threaten childbirth earlier due date, for the prevention of which Ginipral is often prescribed in Russia.

Action Ginipral

Ginipral is a modern tocolytic drug that affects the contractile activity of smooth muscles, reduces muscle tone. The active substance of the drug hexoprenaline selectively stimulates β2-type adrenoreceptors located in all muscles of the body: the uterus, heart, skeletal muscle tissues, as well as in the bronchi, liver and other organs. Ginipral allows you to save pregnancy, delay preterm birth until full-term or for the period necessary to take emergency measures.

Due to the selective (selective) principle of action, side effects from the use of Ginipral are less common compared to non-selective drugs that simultaneously affect different types body tissue receptors.

From what week of pregnancy and why is it prescribed

This tool is actively used to prevent premature birth. Ginipral is used as monotherapy, since its simultaneous use with other similar drugs increases the risk of side effects by several times. The drug is allowed for pregnant women starting from the second half of the second trimester. Earlier than 24–25 weeks, it is ineffective, since the uterine receptors, which are affected by the drug, become sensitive only by this time.

Normal tone in the first half of pregnancy is supported by hormonal therapy.

Increased uterine tone and other indications for droppers and tablets

Ginipral tablets are prescribed once or as a course for women with increased tone uterus with premature smoothing and opening of the cervix as a means to prevent early birth. Usually they are used to continue therapy after a course of intravenous administration of a solution, but they can also be used separately from it - on an outpatient basis, that is, at home.

In a hospital, if a woman is placed in storage or brought to the hospital by ambulance, a solution is prescribed for intravenous administration through droppers. If 48 hours after the start of treatment there is no recurrence of contractions, then the pregnancy continues to be maintained by taking Ginipral in the form of tablets.

IN special occasions tablets and droppers are prescribed simultaneously: the tablet is taken shortly before the end of the intravenous solution.

In the case of childbirth, yet begun ahead of time, Ginipral solution is prescribed:

• for the prevention of contractions, when there are strong and very frequent uterine contractions without smoothing the cervix or opening the pharynx;
• to inhibit contractions with a smoothed cervix and / or opening of the cervix of the uterus;
• as an emergency measure before taking the pregnant woman to the hospital.

The drug is also used during timely delivery in order to stop contractions in the following situations:

• with obstructed blood flow to the fetus;
• with prolapse of the umbilical cord;
• with complicated labor activity;
• before caesarean section;
• before fetal rotation transverse position to relax the muscles of the uterus.

The use of Ginipral as a means of relaxing the muscles of the uterus is also necessary in the case of suturing the short neck before the operation, during and after the procedure.

The drug is administered very slowly, about 5-6 hours.

What the experts say

Among all the available tocolytics intended to prevent preterm labor and maintain pregnancy, most domestic specialists prefer beta2-adrenergic agonists, in particular, Ginipral.

Based on the long-term use of Ginipral, it has been established that the effectiveness of its use is about 90%.

Serov V. N., Tyutyunnik V. L., publication in Russian medical journal

http://www.rmj.ru/articles/pediatriya/Taktika_lecheniya_ugroghayuschih_preghdevremennyh_rodov/#ixzz4FVFgXzN7

Despite popular belief, doctors say that the drug does not affect the course of childbirth. After its cancellation, the possibility of natural delivery without complications returns to the woman.

Contraindications

The appointment of hexoprenaline is prohibited for women with:

• thyrotoxicosis;
• tachyarrhythmias;
• myocarditis;
• mitral valve disease and aortic stenosis;
• ischemic heart disease;
• arterial hypertension;
• severe diseases of the liver and kidneys;
• angle-closure glaucoma;
• uterine bleeding, premature detachment placenta;
• chorioamnionitis and other intrauterine infections;
• I trimester of pregnancy;
• lactation (breastfeeding);
• hypersensitivity to the components of the drug (especially in patients with bronchial asthma and history of hypersensitivity to sulfites).

Gap amniotic sac and the opening of the cervix by more than 3 cm greatly reduce the effectiveness of Ginipral.

Side effects and effects on the fetus

During treatment, the following undesirable reactions of the body are possible:

• headache, dizziness;
• feeling of anxiety, trembling fingers;
• decrease in blood pressure, an increase in the heart rate in the mother (while the heart rate in the child, as a rule, does not change), heart rhythm disturbances, chest pain, which disappear after stopping the use of the drug;
• nausea, vomiting, bowel problems, intestinal obstruction, a temporary jump in the level of liver enzymes in the blood;
• difficulty breathing, bronchospasm, pulmonary edema, impaired consciousness up to coma, anaphylactic shock (in patients with bronchial asthma or patients with hypersensitivity to sulfites);
• lack of potassium and calcium at the beginning of therapy, increased blood sugar levels;
• sweating, decrease in the amount of urine produced, edema (especially in patients with kidney disease).

The frequency of side effects directly depends on the dose of the drug, therefore, if the above symptoms appear, it may be necessary to adjust the prescribed treatment.

In a newborn, as a result of the treatment of the mother with Ginipral, the blood sugar level can be reduced, and the acid-base balance of the body is shifted to the acid side.

Despite the many side effects, thanks to Ginipral, it becomes possible to prevent or delay preterm birth for the period necessary to transfer a woman to perinatal center and acceleration of fetal lung maturation.

How to use and properly cancel the drug

Ginipral can be used both for a long time (up to several months) to eliminate the threat of preterm labor, and once, if there are specific indications. The dose of the drug and the treatment regimen is always selected individually.. The doses recommended in the instructions are indicative information for specialists. Reducing the prescribed dose and in the future complete cancellation the drug is produced by a doctor only 5-7 days after the elimination of the threat of abortion, as well as in the case of:

• difficult breathing;
• significant changes in blood pressure, chest pain, suspicion of heart failure;
• hypersensitivity.

It is necessary to cancel the drug not abruptly, but gradually reducing the dose. If you abruptly stop drinking pills, this can lead to the reappearance of uterine hypertonicity.

Risk Mitigation Instructions

Due to the fact that Ginipral has a significant effect on the body as a whole, a number of preventive measures must be taken during treatment.

1. Due to the effect of the drug on cardiovascular system, you need to monitor the pressure and heart rate of both the mother and the fetus. If necessary, the control of the heart is carried out using an ECG.
2. In the first days of treatment, there is a high probability of an increase in blood sugar levels, therefore, in women with diabetes Carbohydrate metabolism indicators are carefully checked to exclude hyperglycemia.
3. Decreased diuresis makes necessary observation for the appearance of symptoms that indicate fluid retention in the body.
   

   During treatment with Ginipral, excessive fluid and salt intake should be limited.

4. Due to the effect on intestinal motility, it is recommended to pay attention to the regularity of the stool.
5. Control of the normal functioning of the lungs, the absence of noise, swelling of the bronchi is needed, since Ginipral also affects the pulmonary muscles.
6. In parallel with Ginipral, potassium preparations and agents for the prevention of heart disorders, for example, Verapamil, are often prescribed.
7. Tea and coffee during treatment with Ginipral may increase the body's adverse reactions to the drug.
8. In case of hypersensitivity to sympathomimetics, Ginipral is prescribed in small doses and with constant monitoring of the woman's condition by the doctor.

Why the doctor can cancel Ginipral and how to replace it

Treatment tactics aimed at preventing preterm labor depend on the duration of pregnancy, the condition of the mother and child, the integrity of the amniotic sac, the nature of contractions of the muscles of the uterus, the degree of readiness of the cervix for childbirth, the presence and severity of bleeding. Depending on these indicators, certain drugs are prescribed.

Ginipral causes many side effects, besides, it must be prescribed carefully due to the impressive list of contraindications. Therefore, some doctors in their practice use drugs based on fenoterol (for example, Partusisten).

Magnesium sulfate (magnesium) known to many is widely used in domestic medicine, despite the absence of a pronounced tocolytic effect. But in guidelines The Ministry of Health of the Russian Federation for the management of preterm labor, it is not recommended as a means of reducing the frequency and intensity of uterine contractions.

Complications during pregnancy are unpredictable. One of dangerous states is uterine hypertonicity, in which there is a threat of miscarriage or premature birth. In a similar situation, women are prescribed the drug ginipral - intravenously or in the form of tablets.

Uterine tone

The uterus during gestation should be in a relaxed state, however, its functioning may be impaired. What is uterine hypertonicity? In this condition, the muscles contract either continuously or intermittently. Why is this happening? Hypertonicity of the uterus may be due to psychological reasons:

• inactive lifestyle;
• bad habits of the expectant mother;
• stress and excessive hassle;
• other reasons.

A pregnant woman should get enough sleep and not overexert herself. Chronic sleep deprivation can cause unplanned uterine contractions. TO harmful influences uterine tone also includes unfriendly relationships in the family, early abortions and early pregnancy(up to 18 years old). Also, hypertonicity can occur in women after 35 years of age during their first pregnancy. Unfavorable factors include influenza, SARS during gestation, inflammatory processes in history.

Also, hypertonicity can be caused by physiological reasons:

• malformations;
• multiple pregnancy;
• endometriosis of the uterus;
• uterine myoma;
• somatic diseases;
• genetic feature;
• immune deficiency;
• endocrine diseases.

Until four weeks of gestation, this pathology is treated with hormonal drugs. At a later date, ginipral is prescribed - intravenously or in tablets. Also, the drug is prescribed during labor with uneven and too intense contractions.

Survey

Untimely contraction of muscle fibers is fraught not only with miscarriage, but also oxygen starvation fetus. Such a pathology affects the normal development of the fetus, prevents the intake of nutrients and can cause irreversible changes.

For a woman, muscle contraction can cause pain, cause bloody issues and make you feel worse. How to independently determine hypertonicity? Symptoms of this pathology are:

• cramping abdominal pain;
• drawing pains in the base of the back;
• a characteristic feeling of tension in the abdomen;
• "petrification" of the abdomen.

If these signs are accompanied by discharge of bloody or Brown pathology is present. An urgent examination is needed, after which the doctor will prescribe ginipral tablets / intravenously.

Medical diagnostic methods include:

1. vaginal examination;
2. hardware research.

Important! Nagging pain in the abdomen is not a symptom of a complication. Pathology is accompanied by other signs of disease or abnormality. Pain in the first half of pregnancy may be due to the growth of the uterus.

Prescribing the drug

Ginipral is prescribed after the 20th week of pregnancy in case of pathology. Pills are taken for prevention uterine contractions, a dropper is placed in case of emergency with the threat of miscarriage. The drug in the form of tablets is taken for a long course of up to two months. In case of improvement in muscle condition, the dosage of the drug is adjusted.

Important! It is forbidden to use the drug ginipral alone during pregnancy without consulting a gynecologist.

The course of therapy is calculated individually. Sometimes the uterus returns to normal after a month of taking the drug, sometimes treatment is required for the entire second half of pregnancy. It depends on the individual state of the woman's organ and the characteristics of the course of pregnancy. With the normalization of the tone of the uterus, the drug is gradually reduced in dosage.

Important! It is forbidden to abruptly stop the use of ginipral in order to avoid recurrence of the complication.

During the course of treatment with Ginipral, the state of the pulse and blood pressure of the woman and fetus should be checked. The doctor prescribes an electrocardiogram to check the mother's cardiac activity, and CTG is performed to monitor the condition of the fetus. With an increase in the woman's pulse, the dosage of the drug is reduced.

Important! The drug ginipral increases blood glucose, so chronic diabetics should measure their sugar levels regularly.

The introduction of the drug during pregnancy reduces the amount of urine excreted. This normal phenomenon. You should not get carried away with liquids to increase the rate of excreted urine: you need to consume liquid in a volume of 2.5 liters in essence.

With the appearance of shortness of breath and disruption of the heart, the drug is immediately canceled. This may be an indicator of a drug overdose. Overdose symptoms are:

• arrhythmia and tachycardia;
• intense sweating;
• trembling of the fingers;
• pressure drop;
• heartache;
• headache.

To eliminate an overdose, antagonists are used - drugs that eliminate the effect of ginipral. These funds are prescribed by the attending gynecologist.

The action of the drug and side effects

The effectiveness of the drug ginipral decreases when interacting with certain medical agents. Ginipral is not prescribed simultaneously with beta-blockers. There was also an increase in the action this medicine when taken together with Theophylline.

The drug reduces the effectiveness of drugs against advanced level blood sugar. When combined with bronchodilators, it produces side effects. Side effects include:

• dizziness and pain in the head;
• decreased bowel tone (constipation);
• intestinal obstruction;
• swelling and decreased urine;
• active sweating;
• anxiety and sleep disturbance;
• disruption of the heart;
• trembling of the fingers.

Also, side effects can be noted in the newborn: bronchospasm, acidosis, etc. Sometimes there is a decrease in labor activity in women in labor who took this drug: they are given stimulation either C-section. However, complications in labor activity are also found in women who did not take ginipral.

Important! Do not drink ginipral tablets with coffee or strong tea in order to avoid increased side effects from the reaction to the drug substances.

Contraindications

In some cases, the appointment of the drug ginipral is prohibited. These include:

• toxic goiter and Graves' disease;
• myocarditis and arrhythmia of the heart muscle;
• malformations and ischemic heart disease;
• high blood pressure;
• chronic liver / kidney disease;
• uterine bleeding;
• genital infections;
• pathology of the placenta;
• allergy to the components of the drug.

Also, the prohibition of prescribing the drug applies to the first trimester of pregnancy and the period of breastfeeding.

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