Papaverine bleeding in the early stages of an IV. How does it work? Indications for the use of suppositories with papaverine

Only a few women manage to avoid taking pills and medications for the entire nine months. Most of them raise serious concerns, since the effect on the fetus has not been fully studied. Papaverine during pregnancy early stages prescribed quite often. Let's consider how to take it correctly, what effect it has on the body of the mother and child, as well as what diseases will be a direct contraindication for treatment.

Read in this article

What does the drug "Papaverine" affect?

The drug belongs to myotropic antispasmodics. Available in the form of suppositories, tablets and ampoules with solution. Its main purpose is to relax smooth muscles and blood vessels. It relieves spasms without affecting the central nervous system. Has a slight sedative effect. Relieves pain in smooth muscles, including the genitourinary system and gastrointestinal tract. Recommended for:

  • hypertonicity of the uterus;
  • spasms of cerebral vessels;
  • angina pectoris;
  • cholecystitis;
  • spastic colitis;
  • bronchospasms;
  • other.

Even though it is prescribed to pregnant women quite often in the first trimester, papaverine should not be taken independently and uncontrolled! There are a number of contraindications that can seriously worsen the mother's condition. For example, reduce already low blood pressure.

When are Papaverine suppositories prescribed to pregnant women?

Mostly doctors prescribe suppositories with papaverine during early pregnancy. The form, which is not the most convenient to take, will help the expectant mother alleviate her condition faster and more effectively than, for example, pills. With uterine tone, it is especially important, since the effect will be achieved in a matter of minutes.

How to insert suppositories correctly

Young mothers are sometimes at a loss where to insert papaverine during pregnancy, and the phrase “ rectal suppositories"causes slight bewilderment. It's simple: the drug is injected into anal hole(in the ass, if in simple language). It is advisable that the woman does not have sharp nails, otherwise there is a risk of injury. To avoid getting confused about how to insert candles correctly, here’s a little instruction:

  1. Before the procedure, wash your hands warm water. Just not when it’s hot, because the candles melt quickly, which will make it difficult to enter. It is also recommended to first keep the drug in the refrigerator. By the way, it also needs to be stored in a cool place.
  2. Open the package by gently pulling different sides halves.
  3. If you need to use only half the dose, then cut the candle in half along the longitudinal seam.
  4. To maintain hygiene, it is recommended to use disposable gloves from the pharmacy.
  5. Take the candle by the edge, point up. To make it easier to insert, moisten the edge with water or drop a little lubricant without Vaseline.
  6. Take a comfortable horizontal position with one leg straight out and the other bent at the knee.
  7. With one hand, open the anus slightly, moving the buttock to the side (lift it up).
  8. Insert the suppository into the rectum, pushing it with your finger to a depth of 2.5-5 cm. Then squeeze the buttocks tightly for a few seconds.
  9. Lie down for 5 minutes so that the papaverine does not jump out.
  10. Wash your hands and throw away used material.

How to insert rectal suppositories correctly

If you still have questions about how to administer papaverine during pregnancy, consult your doctor.

Injections of the drug "Papaverine"

In early pregnancy there is a threat spontaneous abortion or quite high. A young mother should lead not only a healthy, but also a calm lifestyle. But realistically speaking, only a few succeed. Work, nerves, too much active life, sometimes fear and problems with the future dad provoke increased uterine tone. It is in this case that the drug “Papaverine” is prescribed, injections of which during pregnancy help relieve unpleasant symptoms and preserve the fetus. They can be administered both intramuscularly and intravenously.

It is not recommended to give papaverine injections on your own or with the help of friends without special education! The drug may end up in a place not intended for this purpose, which at a minimum will not achieve the desired effect. In addition, it must be administered slowly.

As for tablets, they are prescribed extremely rarely. The thing is that it takes much longer to dissolve in the body and achieve an effect than with candles or injections.

How to take an antispasmodic during pregnancy

Depending on the reason for prescribing the drug, only the doctor will be able to choose the most convenient dosage form and dosage schedule. For example, from papaverine during pregnancy, the use of which is possible only under the condition high performance, can be prescribed in the form of intravenous injections. If it is necessary to relieve vascular spasm, then the doctor can make the following schedule: two to three suppositories per day at equal intervals.

In this case, in each individual case, possible side effects will be taken into account. You don’t need to prescribe the drug yourself! Only an observing doctor knows exactly how much papaverine is allowed during pregnancy!

Even though expectant mothers are often prescribed papaverine during pregnancy, the instructions for its use do not provide 100% confidence in the safety of use. However, many years of observational experience shows that if the recommendations are followed and possible contraindications are taken into account, it is very well tolerated. Already at the very short time Mommy feels relief, her heart rate becomes even, she calms down, which certainly has a beneficial effect on the child.

Side effects from taking papaverine

Like any medicine, regardless of the form of release, the drug “Papaverine” can also have a negative effect on the body of the expectant mother. To possible side effects include:

  • pressure reduction,
  • constipation,
  • drowsiness,
  • nausea,
  • dizziness,
  • increased sweating;
  • heart rhythm disturbance.

Heart failure occurs most often due to rapid intravenous or intramuscular administration. But the remaining effects can be obtained by the mother who independently increases the recommended dose.

Who should not take an antispasmodic?

Those for whom doctors will definitely not prescribe the drug, but will select an analogue, include pregnant women with the following disorders in the functioning of the body:

  • liver diseases;
  • with problems in the thyroid gland;
  • with abnormal bowel movements (frequent constipation);
  • with increased intraocular pressure;
  • with low blood pressure.

If the doctor has prescribed you to take the drug “Papaverine” during pregnancy, then there is no need to worry about the condition of the child. He does not provide any negative impact for fruit! But you cannot prescribe it to yourself even if you suspect or confirmed diagnosis uterine tone. The fact is that in some cases it will not be effective enough. In a hospital setting, the pregnant woman will be prescribed an additional set of medications. If she is treated on her own, then the chance of losing the child greatly increases.

Pregnancy is a wonderful condition, no one will argue with this statement. But often at this time a woman has to take medications that she had never even heard of before. The need for their use is caused by the occurrence of special processes in the body of the expectant mother.

These drugs include, in particular, papaverine.

Papaverine hydrochloride: what is its benefit during pregnancy?

Suppositories with papaverine are prescribed quite often during pregnancy. Papaverine hydrochloride is its main active ingredient. Additionally, the drug contains fats, which help the substance penetrate the body.

This medicine belongs to the group of antispasmodics. It is obtained from the opium poppy. In strict “medical” language, the opium poppy alkaloid has an antispasmodic effect.

Papaverine hydrochloride causes the following changes in the body:

  • - relieves spasms and tension of smooth muscles;
  • - dilates blood vessels;
  • - improves blood flow.

The drug is developed in three forms:

  • - pills;
  • — ampoules for injections;
  • - candles.

Papaverine suppositories are one of doctors’ favorite medications prescribed at any stage of pregnancy. What do papaverine suppositories help with and why do ladies in “ interesting position» is the medicine recommended in this form, and not, for example, in the form of tablets?

Suppositories with papaverine during pregnancy: indications for use

Papaverine hydrochloride (suppositories) is excellent in cases where a person experiences spasms. Let's say it could be painful sensations in the intestines, colic, spasm of the gallbladder and bile ducts.

During pregnancy, the uterus undergoes many changes, which takes ovum and allows him to grow and develop for 9 months. Naturally, for the female body this is stress (and very strong). Periodically, it seems to take the embryo for an alien element and tries to get rid of it: it arises. The reproductive organ tenses, it is ready to open and expel the fetus.

Sometimes this condition is caused by genetic disorders or chromosomal abnormalities in the development of the fetus - then the process cannot be interfered with. A miscarriage follows.

But uterine tone appears from time to time in all women carrying a child under their hearts, including those who subsequently give birth completely normal child. Tone can occur if a woman is very nervous, has done hard physical work, is very tired, or has had an acute respiratory viral infection or other illness.

Important: this condition can be dealt with if you take timely measures!

Papaverine suppositories will help with tone. The instructions for use note that one of the indications is uterine hypertonicity. By relaxing the muscles and relieving tension, suppositories reduce the discomfort of the pregnant woman, the feeling that her stomach is turning to stone disappears, and pain in the lower abdomen (often a symptom of an incipient miscarriage) disappears.

Is it possible to use papaverine suppositories if there is a threat of spontaneous abortion or is it better to resort to potent drugs? The doctor will make the decision. If the situation is serious enough, the woman is hospitalized and given droppers with magnesium sulfate - magnesia, sometimes coupled with the use of suppositories.

Papaverine suppositories during early pregnancy (as well as throughout the entire period of gestation) is a drug that has earned a lot of positive feedback from doctors and patients. But the tablet form, like injections, is not suitable for expectant mothers - they act with too much “power” and speed. The state of pregnancy requires slow absorption of the drug into the blood.

How to use depending on the stage of pregnancy?

How to place papaverine suppositories correctly? And in general, papaverine during pregnancy - how often can you use the medicine so as not to cause any undesirable consequences for the unborn child?

First trimester

If the unpleasant condition occurs once, then you can put candles several times over 2-3 days. Usually, doctors prescribe suppositories for a couple of weeks at the slightest suspicion of a threat of miscarriage in the first trimester. Since the dosage of the medicine is not dangerous for pregnant women (if you use the drug according to the instructions), sometimes the time of use is extended to a month or more.

Second trimester

In the second trimester, the likelihood of spontaneous abortion is less, but it still remains. The reason may lie in insufficient production of progesterone by the mother's body. In this case, doctors also prescribe papaverine suppositories.

They should be used 2 to 4 times a day. How to insert candles? If a woman has ever used suppositories for hemorrhoids, then she will not have any difficulties: the principle is the same. It is necessary to retire, preferably lie on your back and gently insert the suppository into the anus.

You just need to do this quickly enough, because candles melt in your hands under the influence of the heat of the human body.

Third trimester

Papaverine is also used during pregnancy in the third trimester. True, there are different opinions among doctors regarding whether papaverine can be taken in the third trimester. The reason lies in the following: the third part of pregnancy is the time when the mother’s body is slowly preparing for childbirth. During this period, the cervix gradually shortens and smoothes out. Papaverine (suppositories) during pregnancy later can provoke excessive relaxation of the cervix - it will open, and premature birth will follow. Therefore, some gynecologists recommend using suppositories with caution if the moment of birth is still far away.

But at the beginning labor activity- a completely different picture. Papaverine helps before childbirth female body gently prepare for the upcoming test and even slightly numbs contractions. By the way, with its help you can determine whether real contractions have begun: if after the suppository it became easier, the pain went away - it means that this is still only “training”.

Interesting: a woman can use this feature of suppositories to “diagnose” the onset of labor in late pregnancy.

How much do papaverine suppositories cost? Having looked through the websites of pharmacies, you can be convinced that the price is low. On average, a package of 10 suppositories costs 35-50 rubles.

Possible side effects

Papaverine during pregnancy: how often can it be used without fear side effects? In the first and second trimester, courses can be taken for a week or longer. IN last trimester- based on the condition of the cervix. Of course, all this should be done only as prescribed by a doctor.

Side effects when correct use rarely bother women. These include:

  • skin redness;
  • drowsiness;
  • constipation

The drug has almost no contraindications.

Exceptions are severe liver pathologies (liver failure), chronic renal failure in later stages, severe hypothyroidism.

In addition, if a woman has heart problems, she should inform her doctor about this: a heart rhythm disorder such as ventricular tachycardia requires extreme caution when using papaverine.

If a woman knows about her tendency to constantly low blood pressure, then she should also inform the doctor: papaverine has the property of lowering blood pressure.

An overdose of papaverine may cause some apathy, since the medicine has a slight sedative effect. True, when using suppositories it is unlikely to manifest itself - the dose of the active substance is too small. Still, just in case, it’s worth observing your body’s reactions.

Typically, women note only a positive effect, and among the disadvantages they pay attention to the fact that the method of administering the medicine is not very convenient, since it requires the creation of an “intimate environment,” as well as the property of suppositories to quickly melt in the palms.

Drugs - analogues

In addition to papaverine, you can use other means to relieve tone. So, doctors often prescribe no-shpa tablets. The price for the patient will be approximately the same - but the spa will be even cheaper.

(aka drotaverine) is a derivative of papaverine. It can also reduce the tone of the uterus and promote relaxation of smooth muscles. The medicine is known for its ability to gently relieve pain. No-spa is safe and is often prescribed to pregnant and laboring women.

Sometimes doctors opt for valerian. This herbal preparation is also included in the group of drugs that are safe for expectant mothers. In addition to relieving tone, valerian calms and fights overexertion and stress, which are dangerous during pregnancy.

Suppositories with papaverine are not a new drug. It has been tested by experience by more than one generation of expectant mothers. Its safety, low price, and most importantly - effectiveness, have created a good reputation among doctors and patients. If the doctor suspects a threat to the tone of the uterus, if he strongly recommends buying suppositories, then you need to listen to his advice.

Not a single healthy one strong baby was born thanks to this medicine. But if it had not been invented, miscarriages would have occurred much more often, and premature children would have been born, rushing into the world too early. Don't give up on achievements modern medicine: She can do a lot today!

Having learned about her pregnancy, every woman begins to listen to her body. Therefore, any unusual sensation often becomes the reason for a visit to the doctor.

The favorite diagnosis of our doctors, especially in initial stage pregnancy, is increased uterine tone.

Having suspected it, the doctor will immediately prescribe the expectant mother a medicine, which, according to him, is effective and absolutely safe. And such a drug, in most cases, becomes Papaverine.

I propose to find out: is Papaverine really necessary in the early stages of pregnancy or can you do without it?

What kind of drug is Papaverine?

  1. Papaverine is an alkaloid, a synthetic substance obtained from vegetable oils. Once in the bloodstream, it promotes vasodilation, and in a spastic state has an antispasmodic effect;
  2. If the drug is used in large doses, its relaxing effect is noted;
  3. The substance is eliminated from the body after 1-2 hours;
  4. Papaverine is prescribed very often during pregnancy in our country. And, taking into account the diagnosis, the doctor selects the form of the drug (tablets, injections, suppositories with papaverine during pregnancy).
  • The drug in tablet form has a hypotensive and antispasmodic effect and is usually prescribed for a short course in the presence of mild pathologies. In the later stages, it is recommended to take it for heart rhythm disturbances and hypertension;

If you suspect an increased uterine tone, the doctor may prescribe Papaverine as part of complex therapy. This drug is not used on its own.

  • Injections with the drug can be carried out both intramuscularly and intravenously. In the latter case, its administration is allowed only in a hospital setting;
  • The drug in the form of suppositories is the most common prescription when it is detected in an expectant mother. high temperature, blood pressure surges or increased tone uterus.

Although the drug is considered safe, it can only be used under the supervision of a physician, as there is a possibility sharp deterioration condition of a woman.

The regimen of use depends entirely on the diagnosis. This can be either a one-time administration or long-term use.

Why is it prescribed to pregnant women?

Why is Papaverine prescribed in early pregnancy?

The main reason is progesterone deficiency, which leads to uterine hypertonicity. Doctors say that this condition poses a threat and can provoke termination of pregnancy.

And the most common drug in our country prescribed for uterine tone during pregnancy is Papaverine. Also read the current article on the topic: Uterine tone >>>.

Instructions for use of Papaverine during pregnancy indicate that it is prescribed for:

  1. spasm of smooth muscles or genitourinary tract;
  2. vasospasm;
  3. renal colic;
  4. threat of miscarriage;
  5. hypertension;
  6. increased tone of the uterus;
  7. gestosis (read: Preeclampsia during pregnancy >>>).

Thus, this drug is almost always prescribed to women in whom the doctor has diagnosed a pathology that can lead to miscarriage.

Contraindications

It is believed that the components of Papaverine are not able to overcome placental barrier, therefore absolutely safe for the fetus. Although there is still a risk for the mother. An absolute contraindication to the use of the drug is:

  • AV block;
  • glaucoma;
  • liver or kidney failure;
  • hypersensitivity to papaverine.

Sometimes after using the drug, women note side effects:

  1. dizziness, increased drowsiness, migraine;
  2. heart rhythm disturbances, decreased blood pressure;
  3. hives, swelling or even anaphylactic shock;
  4. digestive disorders (constipation, diarrhea, nausea);
  5. liver dysfunction;
  6. visual impairment.
  • redness of the skin;
  • change in heart rate;
  • double vision;
  • diarrhea;
  • a sharp decrease in blood pressure.

It is important to note that Papaverine can cause dizziness in the mother and negatively affect the reaction speed.

How to use? Where should I insert it? How often?

For expectant mothers, Papaverine is mainly prescribed in the form of rectal suppositories, which have an antispasmodic effect. In addition, it reduces arterial pressure, thanks to the ability to dilate blood vessels.

Where is Papaverine inserted during pregnancy?

  1. Suppositories are intended for rectal administration, so they need to be inserted into the rectum after cleansing the intestines;
  2. Here he gradually dissolves, and his active ingredients penetrate the bloodstream and spread throughout the body;
  3. These suppositories are not intended for vaginal administration.

How much Papaverine can you use per day during pregnancy?

  • The dosage of the medicine depends on the specific diagnosis and the degree of development of the pathology. Typically, the doctor recommends using 2 to 4 suppositories per day;
  • The duration of use of the medicine will be individual and depend on general condition a pregnant woman and the symptoms that bother her;
  • Sometimes, to eliminate discomfort, it is enough to use candles for several days. But, in some cases, the course of treatment can be extended to several months.

How often Papaverine can be taken during pregnancy depends on the general condition of the woman. Since doctors are confident in its safety, they can prescribe it quite often if uterine hypertonicity is suspected.

Papaverine – helps or is it a fiction?

After using Papaverine, many women note an improvement in their condition. Their pain in the lower abdomen disappears, their pulse normalizes and anxiety goes away.

But you can get rid of such symptoms without using the drug.

Important! Knowing what doctors mean by the concept of hypertonicity of the uterus, it becomes clear that in most cases this condition is caused by increased agitation, to which many expectant mothers are susceptible, excessive physical exercise or simply a violation of the regime.

Therefore, you can get rid of these symptoms simply by resting, taking a walk outside or drinking a cup of herbal tea (read the article

A considerable number of pregnant women cannot do without pills, injections and even IVs. At the same time, a whole “bag” is often hidden behind the incomprehensible names of medications. side effects for the expectant mother and child. Papaverine is one of the most frequently prescribed drugs during this period. What is its effect on the body and is it safe to use for the woman herself and her unborn baby?

What is Papaverine

If in early pregnancy a woman experiences nagging pain in the lower abdomen, as during menstruation, or pain in the lower back - these may be signs of uterine hypertonicity. In this case, the muscles of the uterus involuntarily contract and are constantly in a tense state. All this can negatively affect the further course of pregnancy.

The main cause of hypertension is a lack of the female sex hormone progesterone, which is also called the “pregnancy hormone”. When it is produced in sufficient quantities in the body of a pregnant woman, it suppresses spasms of the muscles of the uterus, and if it is deficient, there is a risk of miscarriage or premature birth.

Hypertonicity can also be caused by:

  • toxicosis;
  • premature dilatation of the cervix;
  • functional thyroid disorder;
  • Rhesus conflicts;
  • sexual intercourse;
  • stress;
  • nervous tension.

Relieving spasm of the uterine muscles is the main goal of treatment for hypertonicity. And here an effective drug to combat this disease comes to the rescue.

Composition of the drug, its purpose

The drug is based on papaverine hydrochloride, an alkaloid of opium poppy, a substance that relieves spasms of all types of smooth muscles.


Papaverine - effective remedy to relieve spasms of the smooth muscles of the uterus of a pregnant woman

Papaverine received its name back in the 19th century. It comes from the Latin word papever, which means poppy. The drug received this name due to its composition. It was originally made from opium, which is found in large quantities in poppies. When used correctly, it did not have any effect negative influence on the central nervous system.

Ksenia Skrypnik

Vesti channel Medicine"

The main effect of Papaverine is antispasmodic with a wide range of applications. It is used for spasms not only of the uterus, but also of the bronchi, blood vessels and other organs.

Papaverine also has the following properties:

  • sedative;
  • anesthetic;
  • hypotonic.

Use of Papaverine at different stages of pregnancy

The instructions for Papaverine do not say anything about its use for the treatment of pregnant women. However, gynecologists have already accumulated sufficient positive experience in using this medicine during pregnancy.

Expectant mothers should use any medication only as prescribed by a doctor.

The action of Papaverine in the early stages and in the second trimester helps prevent miscarriage, and in the third trimester helps to avoid premature birth. Closer to the date of birth, the indication is to prepare the cervix for dilatation. At the onset of labor, the medicine effectively reduces pain syndrome during contractions in a pregnant woman.

Papaverine does not have a negative effect on the fetus. Children of mothers who took this drug during pregnancy are born healthy and developed.

When I was pregnant with my second child, at thirty-four weeks I was admitted to the hospital with high pressure- 150 to 90. The doctor prescribed me Papaverine intramuscular injections twice a day. My blood pressure returned to normal, and at the thirty-eighth week I gave birth to a healthy son. There were no deviations. After giving birth, my blood pressure returned to normal.

Video: uterine tone during pregnancy

Indications for use for expectant mothers

Papaverine is prescribed to pregnant women for:

  • lowering blood pressure;
  • improving blood supply;
  • relaxation of the smooth muscles of the uterus;
  • reducing high temperature;
  • eliminating the risk of spontaneous miscarriage;
  • relieving colic of a renal, abdominal, hepatic and bronchial nature;
  • dilation of the bronchi and easier breathing.

The purpose of prescribing Papaverine during pregnancy can be different, and the form in which Papaverine will be used depends on it. It is presented in three types:

  • pills;
  • injection;
  • rectal suppositories.

Most efficient look medications for the treatment of expectant mothers are Papaverine in the form of injections and suppositories. The use of Papaverine in the form of tablets for the treatment of pregnant women is not practiced. This is due to the fact that with uterine hypertonicity, a pregnant woman needs emergency care, because the life of the unborn child is at stake. And tablet drugs need a longer period of time to provide therapeutic effect on the body.


When treating pregnant women, Papaverine in tablet form is used very rarely.

Injection

To achieve an immediate therapeutic effect, injections are used: intravenously or intramuscularly. When administered intravenously, the medicine immediately enters the bloodstream and acts instantly. The effect of intramuscular injections occurs a little later, but still much faster than when using tablets or suppositories.
Urgent Care for uterine hypertonicity - Papaverine injections

If, upon examination, the doctor discovers a threat of termination of pregnancy, the woman is admitted to the hospital and she is prescribed intramuscular or intravenous injections of Papaverine.

Papaverine is administered intravenously very slowly. This procedure can only be performed by a specialist - a doctor or nurse.

The woman’s condition will improve significantly within a short period of time after the injection. Future mom she will feel calmer and her heart will begin to beat slower.

When are papaverine suppositories used?

Prescribed to a pregnant woman if the threat of miscarriage is insignificant.
If there is a slight threat of miscarriage, a woman is prescribed Papaverine suppositories.

Candles are used when home treatment and are used as a storage element that maintains the constant condition of the uterus. An improvement in a pregnant woman's condition occurs a few minutes after use: the stomach becomes soft, the pain recedes, and the muscles relax.

My friend became pregnant with her second child at the age of 42. The eldest daughter was twelve years old at that time. After her first child, she was unable to maintain her pregnancy. Before the tenth week, she had miscarriages twice. It’s good that she came across an experienced gynecologist who advised her to use a Papaverine suppository at night from the fourth to the tenth week. Now my friend has an adult second daughter, who was born an absolutely healthy girl.

Contraindications and side effects

Papaverine is usually well tolerated. However, it is contraindicated if a woman has this moment have or had health problems before pregnancy. Namely:

  • thyroid diseases;
  • tachycardia;
  • liver dysfunction;
  • increased eye pressure;
  • bronchial obstruction syndrome;
  • hypersensitivity to the components of the drug.

Also, when treated with Papaverine, the following side effects may occur:

  • from the cardiovascular system:
    • excessive drop in pressure;
    • arrhythmia;
  • from the gastrointestinal tract:
    • nausea;
    • vomit;
    • lower abdominal pain;
    • problems with bowel movements;
  • on the skin:
    • rashes;
    • itchy redness;
  • from common violations:
    • increased sweating;
    • dizziness.

If you experience one of these symptoms expectant mother should stop taking the drug and consult a doctor to adjust treatment.

Table: interaction of Papaverine with other drugs

Features of the use of Papaverine

The use of Papaverine depends on the form of release of the medicine.

Table: method of application and dosage of Papaverine depending on the form of release

Release form Dosage Mode of application
Pills 40 mg 3 times a day Does not depend on food intake. Swallow the tablet whole with plenty of water. For problems with the gastrointestinal tract, take half an hour before meals.
Injection 20–40 mg 2–3 times a day. When administered intravenously, 20 mg (1 ml) is pre-diluted in 20 ml of 0.9% isotonic sodium chloride solution. The interval between injections is at least 4 hours. Intramuscular administration is preferable, intravenous - only when severe course diseases.
Candles 1 candle 2–3 times a day Rectal entry only. Suppositories are introduced at regular intervals.

The duration of treatment is determined by a specialist and depends on the type of pathology. Dosage for pregnant women is prescribed only by a doctor.

The maximum dose of Papaverine also depends on the form of the medicine.

Table: maximum doses of Papaverine

Papaverine analogues allowed during pregnancy

Sometimes, at the discretion of the doctor, instead of Papaverine, another drug is prescribed that is similar in its functions to the body of a pregnant woman. Most often this role is played by:

  • Drotaverine:
    • Spasmol;
    • Spasmonet;
    • Spazoverine;

The main active ingredient of No-shpa is drotaverine. There are two types sold in pharmacies medicine:

  • pills;
  • injection.

The main effect of the drug is to relieve spasms of nervous or muscle origin.


The most famous and popular analogue of Papaverine is No-shpa

Dosage for use of No-shpa:

  • in the form of tablets, the average dose is 120–240 mg per day, divided into 2–3 doses;
  • in the form of an injection solution - 40–240 mg per day, divided into 1–3 separate intramuscular injections.

During pregnancy, it is used to eliminate the tone of the uterine muscles. It is possible to use the medicine for intestinal spasms and headaches.

The main contraindication for the use of No-shpa by a pregnant woman is intolerance to drotaverine. Use with caution in case of liver, kidney or heart failure.

Table: comparison of Papaverine and No-shpa

No-spa is a more modern medicinal product, in its functions it is a copy of Papaverine, but with enhanced and safe action.

Viburkol is a complex homeopathic medicine. Its composition is completely natural.
Viburkol - complex homeopathic medicine

Viburkol is available in the form of suppositories.

The drug has the following properties:

  • analgesic;
  • anti-inflammatory;
  • antispasmodic;
  • sedative.

Expectant mothers are prescribed Viburkol for:

  • increased tone of the uterus;
  • inflammation of the genitourinary system;
  • diseases of the upper respiratory tract;
  • acute respiratory diseases;
  • flatulence.

And thanks to the chamomile and belladonna included in the drug, Viburkol has a calming effect.

Suppositories are used only rectally. For hypertonicity of the uterus, use one suppository in the morning and evening. At mild form To relieve symptoms, use one candle before bedtime. It is not recommended to use Viburcol for more than two weeks.

Suppositories with papaverine have antispasmodic and hypotensive properties. Simply put, they have a relaxing effect on the smooth muscles of a woman’s body during pregnancy.

The antispasmodic properties of the suppository will be helped by a doctor
Papaverine pregnant care
The doctor is exercising his clothes


One of positive aspects is a reduction in voltage internal organs, but there is no similar effect on skeletal muscles. They do not cause weakness in the body.

Indications for prescribing the drug

Among the main indications for use are:

  • decreased uterine tone;
  • improvement of blood flow in the uteroplacental system;
  • vasodilation;
  • elimination of spasms of smooth muscles of the abdominal cavity;
  • improving the functioning of the kidneys, bronchi, and peripheral vessels.

One of the main advantages of a drug based on this basis is its cost. Thus, the price of suppositories during pregnancy is very affordable, and the drug with papaverine can be dispensed without a doctor’s prescription. However, use without permission this drug should not be, as it can be applied irreparable harm baby's health.

These suppositories have antispasmodic properties

Let's consider the reasons for prescribing the drug by trimester.

As you can see, papaverine hydrochloride suppositories have some contraindications during pregnancy. However, in the first stages of expecting a baby, they are used as a remedy that is the safest due to the characteristics of absorption.

In later stages, the effect of such suppositories lasts longer than from other medications due to slower absorption.

Instructions for use

If you have been prescribed this drug, and you do not know where to insert suppositories containing papaverine during pregnancy, carefully read the instructions.

It says:

  • the maximum daily dosage should not exceed 2-3 suppositories;
  • they need to be used at equal time intervals;
  • suppositories are inserted directly into the vagina;
  • The effect of the drug begins immediately after the candle dissolves.

According to the instructions for use for suppositories, this drug during pregnancy has the following properties.

  1. Reduces muscle tension in internal organs.
  2. Reduces blood pressure.
  3. Promotes blood supply to the soft muscles of the uterus.
  4. Has a calming effect.
  5. Stabilizes heart rate.

This product is available in the following forms:

  • injection;
  • pills;
  • rectal suppositories.

Your doctor will help you determine which form of the drug you need.

Select form medicinal product the doctor will help

In the early stages of expecting a baby, priority will definitely be given to rectal medications. Here the doctor must take everything into account individual characteristics patients and indicate how to take papaverine suppositories during pregnancy.

The duration of therapy depends on the situation. As a rule, it is 2-3 weeks, but cases of longer use are known. That is why you should not self-medicate; it is better to consult a doctor.

Very often during pregnancy it is necessary to relieve tension from the internal organs, while leaving the remaining muscles toned, for which suppositories containing papaverine are prescribed. All analgesics have a similar effect, so their combined use is allowed. For example, this drug is often paired with no-spa, but this decision must be made by the attending physician so as not to make things worse.

In later stages, suppositories with papaverine can also be used in combination with other drugs, the range of which is already much wider. For example, therapy with barbiturates enhances the effect of papaverine.

Before using papaverine suppositories during pregnancy, read possible contraindications and side effects:

  • itching sensations may appear, this is due to the vasodilating effect, which is useful for relieving muscle tension, but can be harmful to the skin;
  • excess papaverine can cause blood pressure to drop to values ​​below normal;
  • in exceptional cases, this drug may cause heart rhythm disturbances;
  • Some patients also experience nausea.

Contraindications for use are:

  • low blood pressure;
  • bronchospasms;
  • colic of various natures in case of threatened miscarriage due to hyperactivity of the uterus.

Despite the fact that the product is designed to relieve tension in the uterus, in exceptional cases its use is still not allowed, so you should definitely consult with specialists.

Papaverine has a sedative effect

Opinions and reviews of patients

To find out the opinions of women who have tried the action this tool, here are a few reviews about suppositories with papaverine during pregnancy.

Ekaterina Avdeeva:

She got pregnant pretty quickly. I registered, passed all the tests and was happy with my “situation”. At the next visit to the gynecologist at 20 weeks, the doctor diagnosed a threatened miscarriage. I was prescribed many medications, including this drug. They explained in detail how to take all the medications and where suppositories with papaverine should be administered during pregnancy. As prescribed, I inserted candles at night, in the morning and during the day. The effect followed immediately, I was even surprised, because the drug is quite affordable. The tension in the abdominal area subsided very quickly, and at the next appointment I was told that everything had returned to normal. I am grateful to my doctor and such an excellent drug.