Papaverine bleeding in the early stages of a dropper. Possible side effects. When are papaverine suppositories used?

For pregnant drug Papaverine is that rare but traditional means, which, unlike other drugs, doctors prescribe without fear, as an antispasmodic.

It is produced in the form of rectal suppositories, injections, tablets.

Papaverine solution can be administered intramuscularly, subcutaneously and intravenously, and the doses are selected exclusively individually, taking into account the condition of the pregnant woman.

Indications for the use of papaverine during pregnancy

The tool is used to relieve spasms of cerebral vessels, peripheral vessels and smooth muscles of organs abdominal cavity. during pregnancy, it is prescribed for the threat of premature birth or miscarriage, in addition, with the help of this drug, high blood pressure can be reduced. Papaverine is also able to relieve spasms in case of uterine hypertonicity, produce a sedative effect, reduce arterial pressure. In some cases, when a pregnant woman is in similar conditions, even long courses of treatment with Papaverine can be prescribed.

When do I prescribe papaverine injections?

Although Papaverine is prescribed more often during pregnancy in the form of suppositories, due to its good absorption by the walls of the large intestine, situations are not uncommon when Papaverine injections are also prescribed.

Intravenous injections of papaverine should be carried out exclusively under the supervision of medical professionals, since there are restrictions on the speed of administration of this agent, it must certainly be slow. Intramuscular injections allowed to be carried out at home.

Contraindications

Despite the fact that Papaverine is considered by doctors to be a safe drug that has positive influence on the health of both mother and child, there are a number of contraindications to the use of this drug. In particular, Papaverine is not prescribed to women "in position" who have tachycardia, increased intraocular pressure and there is . The physician must be made aware of the pathological conditions of such kind.

The drug is prescribed with caution and chronic diseases kidneys, adrenal insufficiency and after traumatic brain injury. It's pretty efficient medicinal product, therefore, during pregnancy, it should be used only as directed by a doctor, strictly observing the dosage and treatment regimen.

The use of papaverine injections

When administered intravenously, Papaverine solution should be diluted with saline at the rate of one milliliter of Papaverine solution per ten to twenty milliliters of isotonic sodium chloride solution. This drug must be given slowly because too fast administration may disturb the rhythm of the heart. Between injections, at least four-hour intervals should be observed. A single dose should not exceed one milliliter (twenty milligrams).

Intramuscularly and subcutaneously, Papaverine can be administered up to four times a day, while a single dose should not exceed five milliliters (one hundred milligrams).

Side effects

When using the drug, side effects are possible in the form of headache and drowsiness, and in rare cases there is a possibility of nausea, impaired peristalsis and excessive sweating. Possible manifestations and hypersensitivity to the active substance in the form of allergic reactions. If these symptoms occur, you should immediately notify your doctor.

Treatment with Papaverine is possible only with the exclusion of alcohol, in addition, the effectiveness of this remedy is reduced by smoking.

Pregnancy without any medication, with a glowing smile and good mood- this is something on the verge of fantasy. Usually the environment malnutrition And various diseases that were present before pregnancy leave an imprint on the condition of the woman in position. One of the very unpleasant symptoms is uterine hypertonicity. Usually this condition is the result of insufficient production of progesterone, which makes the muscles of the uterus elastic and smooth. IN similar situations papaverine is attributed to the tone of the uterus. It reduces spasms and reduces the risk of miscarriage from the moment the injection was given.

Why do you need papaverine during pregnancy?

What is papaverine for? His injections have a complex effect and they are prescribed in order to:

reduce blood pressure;
improve blood supply to reduce spasmodic contractions of the muscles of the uterus;
reduce the risk of miscarriage.

Why is papaverine prescribed for pregnant women?

The action is due to the fact that it is an antispasmodic, thanks to which spasm can be removed. Everyone knows that the uterus is also a muscular organ that can contract, thereby causing hypertonicity. Why papaverine relieves spasm? This condition is in combination with other symptoms, for example, if there is low level progesterone, can provoke detachment of the fetal egg.
Also, papaverine can be prescribed in combination with other drugs, if the problems with carrying a pregnancy are large enough. For example, there was bleeding severe pain in the abdomen and other symptoms. If the ultrasound determines that the child's heartbeat is present, then hemostatic drugs are prescribed together with papaverine. And with a lack of progesterone, hormonal drugs may also be prescribed.

Forms of release of papaverine

Papaverine injections during pregnancy are useful not only for a woman, but also for the future of an unborn child. Papaverine can be used in the form of injections, in special suppositories used rectally, and in tablets. An injection of papaverine is easier to administer intramuscularly, and you can use the introduction through a vein, if the patient's condition requires just such a drug intake. And if papaverine injections, which are administered intramuscularly, can be done independently, then intravenous use of the drug must be performed only medical workers, because papaverine during pregnancy should be done as slowly as possible.
Papaverine tablets during pregnancy are not prescribed by specialists so often, they do not act immediately, and you need to wait enough for a long time until they begin to give the desired effect. Candles are more efficient this tool. Where to insert papaverine during pregnancy? Candles are used rectally. The action of the drug in this form is similar to the rate of action of the drug administered intramuscularly.

Dosage and combined use

Usually papaverine on early dates pregnancy is used in a small dosage, which is one candle per day. But if there is any indication, then the medicine can be used up to 3 suppositories per day. But on papaverine during pregnancy, the annotation warns that large dosages of the drug can lead to side effects. Therefore, in the process of taking it is necessary to adhere to the recommendations of the attending physician.

Papaverine during early pregnancy, the dosage of which is relatively low, is a very effective and popular remedy.

But with the course of pregnancy, the action of the drug becomes insufficient. In such cases, papaverine in injections during pregnancy is combined with magnesium sulfate, and such a “cocktail” must be administered intravenously. But in the third trimester, papaverine in tablets during pregnancy becomes completely ineffective. Therefore, it is used together with magnesium. Typically, this combination of drugs is used in cases where there is a shortened and softened cervix. But papaverine intramuscularly in such situations is only part of the complex treatment. IN without fail the woman should be at rest, and at the same time she can be stitched on the cervical canal so that it does not shorten and contract.

Side effects and unwanted effects

Using papaverine tablets during pregnancy, many women may experience certain side effects from taking the drug. And first of all, this is due to the fact that they take it thoughtlessly and not as directed by a doctor. That is, they exceed the recommended dosage, thinking that the medicine is in this case help faster.

Injections during pregnancy can also lead to a number of unwanted reactions, so it is still better to perform all procedures in a medical facility. When using papaverine, the instructions must be read. First of all, you need to know the side effects and consequences of an overdose.

It may be different allergic reactions, severe drowsiness and lowering blood pressure, loss of strength. Hyperhidrosis, loss of appetite, headache, nausea and constipation.

You can use papaverine only as directed by a doctor.

Why is slow administration of papaverine necessary during pregnancy?

If you use the drug very quickly, the normal heart rhythm is disturbed, and this is already fraught with more serious problems for the woman's health.

Papaverine during pregnancy is enough safe drug, but it can be quite dangerous in excess doses. But its danger is manifested only when the drug is taken incorrectly or in high doses. At the same time, the usual dosage is not harmful to either the mother or her unborn child. It is already clear why papaverine is prescribed during pregnancy, why it is used for different terms pregnancy, and what consequences it causes. But in almost all cases, when a woman underwent a course of treatment with papaverine, nothing else threatened the health of her baby.

With the timely use of papaverine, the threat of miscarriage and premature birth is reduced.

Papaverine injections during early pregnancy are enough efficient view treatment. Many years of experience have shown that the medicine makes it possible to endure healthy baby, reduces the risk of spontaneous abortion and premature birth. Papaverine during pregnancy, injections are not used for uterine hypertonicity in some cases. For example, those patients who have liver disease, thyroid gland tachycardia or increased intraocular pressure.

Why are pregnant women prescribed papaverine in the later stages, if childbirth is just around the corner? The fact is that such a drug is able to prepare the cervix for labor activity. But the paradox of this medicine is that in the third trimester it is able to smooth out the consequences of negative factors as much as possible and slow down the processes of uterine muscle contraction.

Candles with papaverine - an alkaloid drug with antispasmodic, hypotensive effect on the rectal area.

The drug helps to weaken smooth muscle cells, relieve spasms in the intestines, eliminate, normalize stools, beneficial effect on vessels and systems in the body.

This is one of the few drugs approved for use by women during pregnancy and breastfeeding. However, contraindications and side effects are available. Before use, it is important to read the instructions, follow the doctor's recommendations.

Release form, composition and packaging

Candles with papaverine - an opium alkaloid with a derivative of the active substance - isoquinol.

ATX code - A03AD01. Issued Russian manufacturers, the company "Dalchimpharm", "JSC Biosintez".

Release forms:

tablets 0.01-0.04 mg in blisters of 10 pieces;
solutions for injection (2%);
ampoules (2 ml) in a carton pack of 10 pieces for subcutaneous, intramuscular, intravenous administration;
rectal suppositories (0.02 g) torpedo-shaped with a smooth white surface for insertion into the rectum.

Packing - contour cells. Additional instructions for use are included.

The composition contains the active substance Papaverine hydrochloride.

The drug has found wide application in gynecology, pediatrics, proctology in the treatment of diseases accompanied by spasms of smooth muscles:

spastic colitis;
cholecystitis;
migraine;
bronchospasm;
renal colic.

With rectal administration of suppositories, there is quick effect and absorption of active ingredients into the bloodstream.

According to experts, papaverine suppositories are the safest form of release.

Consisting of one piece- 20 mg of papaverine hydrochloride (active ingredient) and auxiliary components: sugar, stearic acid, potato starch.

pharmachologic effect

Regardless of the method of administration and form of release, the drug quickly penetrates the body, is absorbed into the bloodstream, binds to plasma proteins up to 90%, passes without difficulty through the histohematological barrier and is transformed in liver cells.

Excreted within 0.5 - 1 hour by the kidneys in the form of metabolic products.

Biotransformation occurs in the liver cells, where inactive decay products are formed and excreted through the rectum.

Active substances are rapidly absorbed into the blood evenly distributed throughout the tissues. Penetrate even into the structures of the central nervous system, affecting the arterial vessels, urogenital tract, muscles of the hepatobiliary and digestive system.

Quickly acting, papaverine suppositories:

expand the lumen of the rectal cavity;
relieve spasms of smooth muscles;
reduce the level of pressure;
reduce the excitability of the heart muscle.

Candles with papaverine have an excellent effect on arterial vessels, the hepatobiliary system, and the structures of the urogenital tract.

They lead to a decrease in the concentration of adenosine monophosphate of calcium ions in the intracellular space, leading to the elimination of spasms in muscle fibers.

Indications for use

Papaverine is widely used in proctology and gynecology in the treatment of diseases as a single drug or in combination with other drugs.

Due to the antispasmodic effect, suppositories are often prescribed in gynecology for women. in the prenatal period with excruciatingly painful contractions to relieve spasms, inflammation, uterine hypertonicity and soften the cervix, which creates a threat of miscarriage.

Also, candles are shown to women with painful periods, and to men - in the treatment of impotence, weak erections.

Candles with papaverine normalize uterine blood flow and pressure indicators, have an antispasmodic effect on blood vessels, eliminate spasms, colic and pain.

Indications for appointment:

Candles with papaverine can be prescribed before surgery to relax smooth muscle structures, performing prostatectomy of the abdominal cavity.

Attention! Candles instantly dissolve and enter the bloodstream, so it is better to use rectally for a reason elevated temperature body in anal area. The effect of oral administration occurs much later.

Recommended form of papaverine- candles in the treatment of diseases: cholecystitis, spastic colitis, spasms urinary tract. Suppositories have fewer contraindications and side effects, unlike other forms of drug release in the composition with Papaverine.

Contraindications for use

The main contraindications to the use of this drug:

It is not recommended to use the medicine in conjunction with nicotine and alcoholic drinks , which can lead to side effects, toxicosis, fainting, increased hypotonic reaction and reduced analgesic effect.

So for smokers in the treatment of hemorrhoids, papaverine can become completely useless and not lead to the proper result.

Side effects

It is important to make sure that there are no contraindications before using suppositories.

Side effects from the respiratory, immune, digestive systems in the elderly are not uncommon:

rash, itching, skin hyperemia;
allergy;
vomit;
dryness, perspiration in the mouth;
arterial hypertension;
ventricular extrasystole;
arrhythmia;
dizziness;
darkening in the eyes;
failure of the heart rhythm;
decrease in blood pressure;
abdominal discomfort;
increased sweating;
excessive dilation of blood vessels.

REFERENCE! Candles with papaverine are considered safe medicine, although you can not self-medicate, especially for women during pregnancy. A feature of Papaverine is instant absorption into the bloodstream and penetration through placental barrier. Any unpleasant manifestations, overstrain of the uterus and colic should be the reason for going to the doctors.

During pregnancy, it is important for women to take into account all the recommendations of a specialist, not to neglect the doses and method of using suppositories. It must be used for its intended purpose, administered correctly if necessary, relieve tension in the uterus.

Stories from our readers!
"For many years I suffered from chronic cystitis. Prescribed drugs made me feel better, and the symptoms went away. But it was only a little bit to catch a cold, as the disease returned again. I decided to seek help from a phytotherapeutist, who advised me herbal collection from cystitis.

Unpleasant symptoms began to disappear already on the second day after the start of the reception. After a month of use, I full examination, which gave negative results. Now I can say with confidence that I have completely got rid of the disease."

Instructions for use

It is important to take into account the age, form of release, dosage, scheme and method of application.

For rectal use, it is advisable to use suppositories at bedtime, carefully insert into the rectum (lumen), for which:

The method of introducing suppositories into the rectum

wash hands with soap;
lie on one side, pull your legs to your stomach;
unpack the candle and insert the straight tip deeper into the anus;
lie down for 0.5 hours without getting up immediately to avoid partial leakage of the candle due to rapid melting.

At correct introduction into the anal passage, the therapeutic effect of the suppository will begin in about 25 minutes

Dosage per day should not exceed 120 mg. Temporal treatment period the average is 10 days, but for the extension should be discussed with the doctor on an individual basis.

Before receiving desired result it is possible to extend the course up to 2 months as needed.

For anal rectal administration the effect and effect on the inflamed focus is observed much faster, in contrast to the tablet form of Papaverine. Overdoses are excluded. The drug is well tolerated and rarely leads to side effects.

As part of rectal suppositories, the dose of papaverine hydrochloride is less. The main thing is to take into account the dosage, clean the rectum beforehand before administering the drug by administering an enema.

REFERENCE! Long term treatment Papaverine is undesirable. Efficiency will gradually decrease and undesirable signs of intoxication may appear: nausea, diarrhea, vomiting, dizziness, allergies, excessive sweating.

For children

When using tablets allowable dose children:

2-4 years - 10 mg 4 times a day;
5-6 years - 10 mg 3 times a day;
7-10 years - 15 mg 4 times a day;
10-14 years - 20 mg 4 times a day.

For rectal administration, the applicable dosage of suppositories with papaverine for adults is 40 mg 2-3 times a day.

A single dose should not exceed 40 mg when administered in solutions (injections) intramuscularly, subcutaneously. When making injections for children - a maximum of 100 mg of a 5% solution and observing a 4-hour interval between injections.

The maximum dose per day should not exceed 500 ml of papaverine solution or 300 mg for children, but taking into account weight and age.

2 years- 20 mg;
4 years- 30 mg;
7-9 years old- 60 mg 3 ml solution;
10-14 years old 100 mg or 5 ml of solution by intramuscular injection, intravenously.

Attention! The drug must be administered slowly. In particular, the elderly with stenosing coronary atherosclerosis. At the same time, pre-measure the pressure indicators. Treatment is recommended to start with minimal doses. Further, in the absence of visible deterioration in well-being, you can gradually increase the dose, unless, of course, the effectiveness is insufficient.

In the treatment of prostatitis in men and the introduction of suppositories into the urethra, the average dose is 40 mg 2 times a day. For the elderly, a single dose should not exceed 100 mg per knock. The course of treatment is 10 days with the possibility of extension, but after consultation with the attending physician.

On a note! Women during pregnancy are not recommended to insert suppositories into the vagina. Only rectal administration of papaverine hydrochloride is allowed, which is unable to show negativism towards the fetus and provoke a miscarriage. Sometimes in medicinal purposes Papaverine is prescribed in injections, but therapy should be carried out exclusively under the supervision of the attending physician.

- the safest form of release of the drug and is often prescribed during pregnancy to women to relieve uterine hypertonicity, prevent premature birth on late term pregnancy, early miscarriage.

It is the overstrain of the uterine cavity that leads to negative consequences.

The drug contributes to:

normalization of blood circulation in the uterine muscles;
stabilization of the heart rate;
decrease in abdominal pressure;
removal of muscle tension;
weakening of the muscles internal organs.

As the fetus grows in the mother's body, one way or another leads to stretching of the walls of the uterus, muscle tension.

It is candles with papaverine that will lead to a weakening of the uterine muscles, while the muscles can no longer relax on their own as the fetus grows.

Candles with papaverine can be a real salvation for women during pregnancy. However, it is impossible to neglect the dosages, advice and recommendations of doctors.

Overdose

immediately, drink a glass of milk, take Activated carbon if side effects are observed 1-2 hours after taking papaverine hydrochloride. It is also important to measure blood pressure.

In case of an excessive drop in indicators, the appearance of vomiting and dizziness, it is better to call an ambulance team without waiting for a deterioration in well-being.

Interaction with other drugs

The combined use of papaverine in conjunction with other drugs may reduce or enhance the therapeutic effect:

Often, drugs are prescribed by obstetricians-gynecologists for uterine hypertonicity, excessive activation of labor, pain in the lower abdomen, and the threat of miscarriage.

But injecting papaverine with anticholinergic drugs is undesirable for Parkinson's disease, neurological disorders in patients due to increased therapeutic effect.

If necessary, replace Papaverine with another analogue, you must first consult with a qualified doctor.

Use during pregnancy and lactation

Candles with papaverine are applicable for women during pregnancy for the following purposes:

risk of miscarriage;
arterial hypertension;
spasms in the bronchi;
heat;
uterine hypertonicity;
colic (renal, intestinal, hepatic) to relax the excretory ducts, restore functions in the body, relieve pain.

According to the instructions for use, the dosage of the drug, taking into account the duration of pregnancy, is somewhat different:

Attention! At severe toxicosis in the 1st trimester, it is highly undesirable for women to take Papaverine in tablets.

Application in childhood

Main indications for use:

babies up to 1 year old- renal colic, endotheritis angina pectoris, intestinal colic, spasms of cerebral vessels;
children from 3 years old- spasms of the urethra, hepatic colitis, pancreatitis, bronchospasm, hyperthermia with spasms of blood vessels in the periphery, high body temperature as an antipyretic.

Sometimes Papaverine is prescribed to babies before the operation.

There are contraindications when using Papaverine tablets:

children under 6 months;
liver failure;
excessive hypersensitivity to the active substance.

Careful use requires the drug for traumatic brain injury, adrenal dysfunction, hypothyroidism. Possible side effects: pressure surges, nausea, vomiting, constipation, drowsiness, excessive sweating.

The dose for children should be observed according to age. If tablets are used, it is undesirable to chew them. It is important to swallow them whole. drinking water. If injections are used, then a single dose for children from a year is 300mg.

The introduction should be done slowly enough to avoid blockade, failure of the functions of the heart muscle.

Acceptable dosages for children, taking into account age:

0.5 - 2 years - 5 mg, 1/4 tablet;
3-4 years - 10 mg, 1/2 tablet;
5-6 years - 12 mg, 1 tablet;
7-9 years - 15 mg, 1.5 tablets;
10-14 years - 20 mg, 2 tablets.

special instructions

Before use, be sure to read the instructions, do not neglect the advice and recommendations of doctors. Treat with caution this medicine with kidney disease, liver failure. Do not be treated with suppositories and take alcohol together.

As part of candles with papaverine - active ingredients with a rapid effect on the central nervous system, therefore, for the period of treatment, it is recommended to step back from driving a car and work that requires increased concentration attention.

Cautious use requires suppositories with papaverine for the following disorders in the body:

adrenal hyperplasia;
hyperthyroidism of the thyroid gland;
chronic renal failure;
violation of the functional activity of the kidneys;
tachycardia;
enlargement of the prostate gland in men;
multiple organ failure.

Caution should be used in pregnant women if the degree of benefit and safety for the fetus is not revealed. In particular, when breastfeeding, it is not advisable to use the medicine on your own without the appointment of a specialist.

Storage conditions and shelf life

Candles with papaverine should be stored in a tight container, dry together, protected from contact. sun rays. Optimum temperature+ 25 degrees.

After the expiration date, candles should be thrown away, and you can not store for a long time in open form, no packaging.

Price

The average price for 1 pack of tablets is 10 pieces 35-40 rub. Injections, 2 ml ampoules – 10 ampoules – 158 rub.

Analogues

You can replace suppositories with papaverine with similar preparations in the composition with drotaverine hydrochloride for the following:

No-shpa to relieve spasm, relax the smooth muscles of blood vessels and internal organs. This is an excellent antispasmodic, recommended for women during pregnancy at any time. In the composition - the active substance (drotaverine hydrochloride). Indications for use: failure of the immune, digestive and of cardio-vascular system. Do not take with hepatic, cardiac and kidney failure. The cost of the drug 60-85 rub. per pack (10 pieces).
Drotaverine with the active substance in the composition (drotaverine). Release form - tablets. Indications for use: disorders of the cardiovascular, nervous, respiratory systems. Contraindications: renal and hepatic insufficiency. Price - 110 rub for 1 pack.
Spasmolysin with pain in the anus, treatment of diseases: cystitis, colitis. Release form - suppositories. Price - 158-163 rub.
spaskuprel to relax the smooth muscle muscles of internal organs, in the treatment of diseases of the kidneys, intestines, stomach, pancreas. Price - 210-230 rub.
with the appointment of IBS, colic in the intestines, liver, kidneys, treatment of pathologies of the digestive system. Price - 87-95 rub.

It is necessary to use these analogues only with the permission of the attending physician and only after the examination, testing.

Despite the safety of suppositories with papaverine, self-medication is excluded. Wrong dosages, uncontrolled methods of application can cause an ambiguous reaction in the body, lead to negative side effects.

A considerable number of pregnant women cannot do without pills, injections and even droppers. At the same time, a whole “bag” is often hidden behind the incomprehensible names of medicines. side effects For future mother and a child. Papaverine is one of the most commonly prescribed drugs during this period. What is its effect on the body and is it safe to use for the woman herself and her unborn baby?

What is papaverine

If in early pregnancy a woman experiences pulling pain in the lower abdomen, as during menstruation, or back pain - these may be signs of uterine hypertonicity. At the same time, the muscles of the uterus involuntarily contract and are constantly in a tense state. All this can adversely affect the further course of pregnancy.

The main cause of hypertension is the lack of the female sex hormone progesterone, which is also called the “hormone of pregnancy”. When it is produced in sufficient quantities in the body of a pregnant woman, it suppresses spasms of the muscles of the uterus, and if it is deficient, there is a threat of miscarriage or premature birth.

Also, the cause of hypertension can be:

toxicosis;
premature opening of the cervix;
functional disorder of the thyroid gland;
rhesus conflicts;
sexual intercourse;
stress;
nervous tension.

Removing spasm of the muscles of the uterus is the main task of treatment for hypertonicity. And here comes to the rescue - effective medicine to combat this disease.

The composition of the drug, its purpose

The drug is based on papaverine hydrochloride, an opium poppy alkaloid, a substance that relieves spasm of all types of smooth muscles.

Papaverine - effective remedy to relieve spasms of the smooth muscles of the uterus of a pregnant woman

Papaverine got its name back in the 19th century. It comes from the Latin word papever, which means "poppy" in translation. The name of the drug was due to its composition. Initially, it was made from opium, which is found in large quantities in the poppy. When used correctly, it did not negative impact to the central nervous system.
Ksenia Skrypnik

Channel "Vesti. Medicine"

The main action of Papaverine is antispasmodic with a wide range of applications. It is used for spasms not only of the uterus, but also of the bronchi, blood vessels and other organs.

Papaverine also has properties:

sedative;
anesthetic;
hypotonic.

The use of papaverine at different stages of pregnancy

The instructions for Papaverine do not say anything about its use for the treatment of pregnant women. However, gynecologists have already accumulated sufficient positive experience on the use of this medication during childbearing.

Expectant mothers should use any drug only as directed by a doctor.

The action of Papaverine in the early stages and in the second trimester helps prevent miscarriage, and in the third - to avoid premature birth. Closer to the date of birth, the indication is the preparation of the cervix for disclosure. At the onset of labor, the drug effectively reduces pain syndrome during contractions in a pregnant woman.

Papaverine does not have a negative effect on the fetus. Children of mothers who took this drug during pregnancy are born healthy and developed.

When I was pregnant with my second child, I was admitted to the hospital at thirty-four weeks high pressure- 150 to 90. The doctor gave me injections of Papaverine intramuscularly twice a day. The pressure returned to normal, and at the thirty-eighth week I gave birth to a healthy son. There were no deviations. After giving birth, the pressure returned to normal.

Video: uterine tone during pregnancy

Indications for the appointment of expectant mothers

Papaverine for pregnant women is prescribed for:

lowering blood pressure;
improve blood supply;
relaxation of the muscles of the smooth muscles of the uterus;
reduction of high temperature;
eliminate the risks of spontaneous miscarriage;
removal of colic of the renal, abdominal, hepatic and bronchial nature;
expanding the bronchi and facilitating the process of breathing.

The purpose of prescribing Papaverine during pregnancy may be different, and it depends on it in what form Papaverine will be used. It is presented in three types:

pills;
injection;
rectal suppositories.

The most effective type of medicine for the treatment of expectant mothers is Papaverine in the form of injections and suppositories. The use of papaverine in the form of tablets for the treatment of pregnant women is not practiced. This is due to the fact that with uterine hypertonicity, a pregnant woman needs emergency care, because the life of the unborn child is at stake. And tablet preparations need a longer period of time to provide therapeutic effect on the body.

In the treatment of pregnant women, Papaverine in the form of tablets is used very rarely.

Injection

To achieve an immediate therapeutic effect, injections are used: intravenously or intramuscularly. The drug, when injected intravenously, immediately enters the bloodstream and acts instantly. The effect of intramuscular injections comes a little later, but still much faster than when using tablets or suppositories.
Urgent Care with hypertonicity of the uterus - papaverine injections

If during the examination the doctor finds a threat of termination of pregnancy, the woman is placed in a hospital, and she is prescribed intramuscular or intravenous injections of Papaverine.

Intravenous Papaverine is administered very slowly. This procedure can only be performed by a specialist - a doctor or a nurse.

The condition of the woman in a short period of time after the injection will improve significantly. The expectant mother will feel calmer, and her heart will begin to beat more slowly.

When are papaverine suppositories used?

They are prescribed to a pregnant woman if the threat of termination of pregnancy is insignificant.
With a slight threat of abortion, a woman is prescribed Papaverine suppositories

Candles are used for home treatment and are used as a storage element that maintains a constant state of the uterus. Improving the condition of a pregnant woman occurs a few minutes after application: the stomach becomes soft, the pain recedes, the muscles relax.

My friend got pregnant with her second child at the age of 42. The eldest daughter at that time was twelve years old. After the first child, she could not keep the pregnancy. She miscarried twice before the tenth week. It’s good that she came across an experienced gynecologist who advised her to use a Papaverine candle at night from the fourth to the tenth week. Now a friend has a grown-up second daughter, who was born an absolutely healthy girl.

Contraindications and side effects

Papaverine is usually well tolerated.. However, it is contraindicated if the woman has this moment have or had health problems before pregnancy. Namely:

thyroid disease;
tachycardia;
liver dysfunction;
increased eye pressure;
bronchial obstruction syndrome;
hypersensitivity to the components of the drug.

Also, during the treatment with Papaverine, the following side effects can be observed:

from the cardiovascular system:
- excessive pressure drop;
- arrhythmia;
from the gastrointestinal tract:
- nausea;
- vomit;
- lower abdominal pain;
- problems with bowel movements;
on the skin:
- rashes;
- itchy redness;
of common violations:
- increased sweating;
- dizziness.

If one of these symptoms occurs future mother should stop taking the drug and consult a doctor to adjust the treatment.

Table: interaction of Papaverine with other drugs

Features of the use of Papaverine

The use of Papaverine depends on the form of release of the drug.

Table: method of application and dosage of Papaverine, depending on the form of release

Release form	Dosage	Mode of application
Pills	40 mg 3 times a day	Does not depend on food intake. Swallow the tablet whole, drink plenty of water. For problems with the gastrointestinal tract, take half an hour before meals.
Injection	20-40 mg 2-3 times a day. When administered intravenously, 20 mg (1 ml) is preliminarily diluted in 20 ml of 0.9% isotonic sodium chloride solution.	The interval between injections is at least 4 hours. Intramuscular administration is preferable, intravenous - only with severe course diseases.
Candles	1 suppository 2-3 times a day	Rectal only. Candles are introduced at regular intervals.

The duration of treatment is determined by a specialist and depends on the type of pathology. The dosage for pregnant women is prescribed only by a doctor.

The maximum dose of Papaverine also depends on the form of release of the drug.

Table: maximum doses of Papaverine

Papaverine analogues allowed during pregnancy

Sometimes, at the discretion of the doctor, instead of Papaverine, another drug is prescribed that is similar in its functions to the body of a pregnant woman. Most often in this role are:

Drotaverine:
- Spasmol;
- Spazmonet;
- Spazoverin;

The main active ingredient of No-shpy is drotaverine. Pharmacies sell two types of medicines:

pills;
injection.

The main effect of the drug is the removal of spasm of nervous or muscular origin.

The most famous and popular analogue of Papaverine is No-shpa

Dosage of No-shpa application:

in the form of tablets, the average dose is 120-240 mg per day, divided into 2-3 doses;
in the form of a solution for injection - 40-240 mg per day, divided into 1-3 separate injections intramuscularly.

During pregnancy, it is used to eliminate the tone of the uterine muscles. It is possible to use the medicine for intestinal spasms and headaches.

The main contraindication for the use of No-shpa by a pregnant woman is intolerance to drotaverine. Use with caution in hepatic, renal or heart failure.

Table: comparison of Papaverine and No-shpa

No-shpa is a more modern drug, in terms of its functions it is a copy of Papaverine, but with enhanced and safe action.

Viburkol is a complex homeopathic preparation. Its composition is completely natural.
Viburkol is a complex homeopathic preparation

Viburkol is produced in the form of candles.

The drug has the following properties:

analgesic;
anti-inflammatory;
antispasmodic;
sedative.

Expectant mothers are prescribed Viburkol for:

increased tone of the uterus;
inflammation of the genitourinary system;
diseases of the upper respiratory tract;
acute respiratory diseases;
flatulence.

And thanks to the chamomile and belladonna included in the preparation, Viburkol has a sedative effect.

Candles are used only rectally. With hypertonicity of the uterus, one suppository is used in the morning and in the evening. At mild form to relieve symptoms, use one suppository at bedtime. It is not recommended to use Viburcol for more than two weeks.

Pregnancy is the brightest period in a woman's life, so you need to carefully listen to the recommendations of doctors and follow all their instructions.

Reasons for prescribing the drug "Papaverine"

Most common cause going to the doctor in early pregnancy is an increase in the tone of the uterus. This condition is fraught with miscarriage and premature birth. Fine female hormone progesterone controls uterine smooth muscle spasms, but many women suffer from a lack of it. To correct the level of progesterone, drugs are prescribed, such as Duphaston or Utrozhestan. At the same time, antispasmodics are indicated.

The effect of the drug on pregnancy

Most often, to relieve spasms in pregnant women, the drug "Papaverine" is used. Candles with papaverine during pregnancy relax the smooth muscle fibers of the internal organs, optimize the blood supply to the uterus and reduce high blood pressure. In large doses, the drug has a sedative and sedative effect and reduces heart rate. All this has a positive effect on the health of the baby and the expectant mother.

Purpose of the drug "Papaverine" and its use

Assign it in the form of suppositories or injections. For intravenous administration, it is diluted in isotonic sodium chloride solution. However, this method is used only in the clinic under the supervision of a physician. At home, you can make papaverine injections during pregnancy intramuscularly or subcutaneously at a dose of 1-2 ml up to 4 times a day. by the most in a safe way injections are suppositories, or suppositories, as they are also called. Enter 1 suppository rectally up to three times a day. If papaverine suppositories are administered continuously during pregnancy, hypotension, allergic reactions, nausea, constipation, dizziness, and sweating may occur. With intravenous use in a hospital, it is necessary to control the heart rate. It should be noted that side effects do not affect the condition of the fetus. Candles with papaverine during pregnancy have been used for about half a century, during this time no teratogenic or mutagenic effect has been recorded.

Contraindications of the drug "Papaverine"

Despite the fact that papaverine suppositories are well tolerated during pregnancy, they are not prescribed for diseases of the liver, thyroid gland, tachycardia and glaucoma. An absolute contraindication is individual intolerance to the drug.

Means "Papaverine" is considered an over-the-counter drug, but you need to take suppositories with papaverine during pregnancy only as directed by a doctor. It is likely that the doctor will select several drugs to achieve a stable therapeutic effect, and their intake will be carried out according to an individual scheme.

Much attention should be paid to the lifestyle of the expectant mother. As a preventive measure for various complications, keep a sleep schedule, eat right and stick to moderate physical activity. Let it be yoga for pregnant women, Pilates or aqua fitness. However, if the doctor in your particular condition prescribes a strict bed rest, then you need to do everything exactly. The doctor's recommendations depend on the overall picture of the course of pregnancy, previous diseases and many other factors. Follow the doctor's recommendations, and you and your baby will succeed!